Synthesis and structure-activity relationships of a series of (1H-pyrazol-4-yl)acetamide antagonists of the P2X7 receptor
High-throughput screening identified compound 1 as a potent P2X7 receptor antagonist suitable for lead optimisation. Structure-activity relationships (SAR) of a series of (1H-pyrazol-4-yl)acetamides were investigated and compound 32 was identif
Chambers, Laura J.,Stevens, Alexander J.,Moses, Andrew P.,Michel, Anton D.,Walter, Daryl S.,Davies, David J.,Livermore, David G.,Fonfria, Elena,Demont, Emmanuel H.,Vimal, Mythily,Theobald, Pam J.,Beswick, Paul J.,Gleave, Robert J.,Roman, Shilina A.,Senger, Stefan
scheme or table
p. 3161 - 3164
(2010/09/10)
SEARCH FOR ANTIALCOHOLIC AGENTS IN THE SERIES OF AMIDES OF SUBSTITUTED PYRAZOLE-4-CARBOXYLIC AND PYRAZOLE-4-ACETIC ACIDS
-
Zagorevskii, V. A.,Vlasova, N. V.,Zykov, D. A.,Kirsanova, Z. D.
p. 684 - 689
(2007/10/02)
More Articles about upstream products of 125103-53-9