125173-80-0Relevant articles and documents
DNA-directed alkylating agents. 1. Structure-activity relationships for acridine-linked aniline mustards: Consequences of varying the reactivity of the mustard
Gourdie,Valu,Gravatt,Boritzki,Baguley,Wakelin,Wilson,Woodgate,Denny
, p. 1177 - 1186 (2007/10/02)
A series of DNA-targeted aniline mustards have been prepared, and their chemical reactivity and in vitro and in vivo cytotoxicity have been evaluated and compared with that of the corresponding simple aniline mustards. The alkylating groups were anchored