1251834-02-2

Basic information

• Product Name: 1H-Indole-7-carboxaldehyde, 3-iodo-
• Synonyms: 1H-Indole-7-carboxaldehyde, 3-iodo-;3-Iodo-1H-indole-7-carbaldehyde
• CAS NO: 1251834-02-2
• Molecular Formula: C9H6INO
• Molecular Weight: 271.05451
• Mol File: 1251834-02-2.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1H-Indole-7-carboxaldehyde, 3-iodo-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-7-carboxaldehyde, 3-iodo-(1251834-02-2)
• EPA Substance Registry System: 1H-Indole-7-carboxaldehyde, 3-iodo-(1251834-02-2)

Safety Data

• Hazardous Substances Data: 1251834-02-2(Hazardous Substances Data)

Usage

Appearance

Yellow crystalline solid

Derivative

Heterocyclic compound indole

Usage

Building block in organic synthesis (preparation of pharmaceuticals and biologically active compounds)

Usage

Development of fluorescent probes and dyes for biological imaging applications

Therapeutic potential

Studied for potential in treating various diseases, including cancer and neurological disorders.

Upstream product

• 1074-88-0 1H-indole-7-carbaldehyde 

Downstream Products

• 1373134-55-4 (6S,9aS)-2-allyl-N-benzyl-6-(4-hydroxybenzyl)-8-((1-methyl-3-(6-(3-phenylureido)pyridine-3-yl)-1H-indol-7-yl)methyl)-4,7-dioxooctahydro-1H-pyrazino[2,1-c][1,2,4]-triazine-1-carboxamide 
• 1373137-85-9 (6S,9aS)-2-allyl-8-((3-(6-aminopyridin-3-yl)-1-methyl-1H-indol-7-yl)methyl)-N-benzyl-6-(4-(tert-butoxy)benzyl)-4,7-dioxooctahydro-1H-pyrazino[2,1-c][1,2,4]triazine-1-carboxamide 
• 1373134-54-3 (6S,9aS)-2-allyl-N-benzyl-6-(4-hydroxybenzyl)-8-((3-(4-(3-(6-methoxypyridin-3-yl)ureido)phenyl)-1-methyl-1H-indol-7-yl)methyl)-4,7-dioxooctahydro-1H-pyrazino[2,1-c][1,2,4]-triazine-1-carboxamide 
• 1373137-84-8 (6S,9aS)-2-allyl-8-((3-(4-aminophenyl)-1-methyl-1H-indol-7-yl)methyl)-N-benzyl-6-(4-(tert-butoxy)benzyl)-4,7-dioxooctahydro-1H-pyrazino[2,1-c][1,2,4]triazine-1-carboxamide 
• 1251834-08-8 C₃₈H₄₃IN₆O₄ 
• 1251834-06-6 C₂₉H₄₀IN₃O₄ 
• 1251834-05-5 C₄₄H₅₀IN₃O₆ 

Relevant articles and documents

NOVEL COMPOUND OF A REVERSE-TURN MIMETIC AND A PRODUCTION METHOD AND USE THEREFOR

This invention relates to novel compounds of reverse-turn mimetics, having pyrazino-triazinone as a basic framework, and a method of preparing the same, and the use thereof to treat diseases such as cancer, in particular, acute myeloid leukemia.

NOVEL COMPOUNDS OF REVERSE-TURN MIMETICS, METHOD FOR MANUFACTURING THE SAME AND USE THEREOF

Disclosed are novel reverse turn mimetics based on the framework of pyrazino-triazinone, and the use thereof in the treatment of cancers, particularly, acute myeloid leukemia. A method is also provided for manufacturing the reverse turn mimetics on a mass scale.

NOVEL COMPOUNDS OF REVERSE-TURN MIMETICS, METHOD FOR MANUFACTURING THE SAME AND USE THEREOF

Disclosed are novel reverse turn mimetics based on the framework of pyrazino-triazinone, and the use thereof in the treatment of cancers, particularly, acute myeloid leukemia. A method is also provided for manufacturing the reverse turn mimetics on a mass scale.