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(P-CHLORO-PHE5,8)-BRADYKININ is a modified form of the peptide hormone bradykinin, which is known for its role in regulating blood pressure and inflammation. This variant features a chlorinated phenylalanine residue at positions 5 and 8, which can potentially modify its pharmacological properties. The alteration in its structure has been the subject of research to explore its therapeutic effects, such as its ability to induce pain and inflammation, and its potential applications in drug delivery and receptor targeting.

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  • Bradykinin,5-(4-chloro-L-phenylalanine)-8-(4-chloro-L-phenylalanine)- (9CI)

    Cas No: 125229-63-2

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  • 125229-63-2 Structure
  • Basic information

    1. Product Name: (P-CHLORO-PHE5,8)-BRADYKININ
    2. Synonyms: (P-CHLORO-PHE5,8)-BRADYKININ;[(PCL)PHE5,8] BRADYKININ;ARG-PRO-PRO-GLY-P-CHLORO-PHE-SER-PRO-P-CHLORO-PHE-ARG;ARG-PRO-PRO-GLY-P-CHLORO-PHE-SER-PRO-P-CHLORO-PHE-ARG-ACETATE;ARG-PRO-PRO-GLY-(PCL)PHE-SER-PRO-(PCL)PHE-ARG;BRADYKININ (P-CHLORO-PHE5,8);(H-PHE(4-CL)5,8)-BRADYKININ;H-ARG-PRO-PRO-GLY-P-CHLORO-PHE-SER-PRO-P-CHLORO-PHE-ARG-OH
    3. CAS NO:125229-63-2
    4. Molecular Formula: C50H71Cl2N15O11
    5. Molecular Weight: 1129.1
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 125229-63-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: -15°C
    8. Solubility: N/A
    9. CAS DataBase Reference: (P-CHLORO-PHE5,8)-BRADYKININ(CAS DataBase Reference)
    10. NIST Chemistry Reference: (P-CHLORO-PHE5,8)-BRADYKININ(125229-63-2)
    11. EPA Substance Registry System: (P-CHLORO-PHE5,8)-BRADYKININ(125229-63-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 125229-63-2(Hazardous Substances Data)

125229-63-2 Usage

Uses

Used in Medical Research:
(P-CHLORO-PHE5,8)-BRADYKININ is used as a research compound for investigating its potential therapeutic effects. The chlorinated phenylalanine residues at positions 5 and 8 may confer unique properties that could be harnessed for medical applications.
Used in Drug Development:
(P-CHLORO-PHE5,8)-BRADYKININ is used as a candidate in drug development, particularly for its potential to induce pain and inflammation. The modified peptide may offer new avenues for the treatment of conditions related to these symptoms.
Used in Drug Delivery Systems:
(P-CHLORO-PHE5,8)-BRADYKININ is used as a component in drug delivery systems, where its ability to target specific receptors could enhance the efficacy of therapeutic agents. The modified peptide may improve the delivery and bioavailability of drugs, leading to better therapeutic outcomes.
Used in Targeting Specific Receptors:
(P-CHLORO-PHE5,8)-BRADYKININ is used as a targeting agent for specific receptors in the body. The structural modifications may allow for more precise interactions with certain biological targets, which could be beneficial in the development of targeted therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 125229-63-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,2,2 and 9 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 125229-63:
(8*1)+(7*2)+(6*5)+(5*2)+(4*2)+(3*9)+(2*6)+(1*3)=112
112 % 10 = 2
So 125229-63-2 is a valid CAS Registry Number.

125229-63-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (P-CHLORO-PHE5,8)-BRADYKININ

1.2 Other means of identification

Product number -
Other names ARG-PRO-PRO-GLY-P-CHLORO-PHE-SER-PRO-P-CHLORO-PHE-ARG

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:125229-63-2 SDS

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