Functionalized chiral ionic liquid catalyzed asymmetric SN1 α-alkylation of ketones and aldehydes
Pyrrolidine-derived functionalized chiral ionic liquids (FCILs) have been found to catalyze asymmetric SN1 α-alkyl-ations of ketones and aldehydes with up to 99% yield, >99:1 dr and 87% ee. The FCIL catalysts enable SN1 α-alkylations