Second generation CaSH (Camphor Sulfonyl Hydrazine) organocatalysis. asymmetric diels-alder reactions and isolation of the catalytic intermediate
In one step, the well known chiral auxiliary, Oppolzer's camphor sultam, is turned into the new generation camphor sulfonyl hydrazine (CaSH II) organocatalyst. With the primary hydrazine functionality external to the tricyclic structure, CaSH II is active
Li, Qinghua,Wong, Wai-Yeung,Chan, Wing-Hong,Lee, Albert W. M.