125412-04-6 Usage
Uses
Used in Pharmaceutical Industry:
D-Alanine, N-(2-hydroxyethyl)(9CI) is used as a building block for the synthesis of peptides due to its ability to contribute to the formation of the peptidoglycan layer in bacterial cell walls, which is crucial for maintaining cell structure and integrity.
Used in Antimicrobial Agents Development:
D-Alanine, N-(2-hydroxyethyl)(9CI) is used as a key component in the development of antimicrobial agents, leveraging its role in bacterial cell wall synthesis to potentially disrupt bacterial growth and function.
Used in Drug Delivery Systems:
D-Alanine, N-(2-hydroxyethyl)(9CI) is used as a hydrophilic linker in the synthesis of various pharmaceutical compounds, enhancing the hydrophilic character of the molecules and improving their solubility and delivery within biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 125412-04-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,4,1 and 2 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 125412-04:
(8*1)+(7*2)+(6*5)+(5*4)+(4*1)+(3*2)+(2*0)+(1*4)=86
86 % 10 = 6
So 125412-04-6 is a valid CAS Registry Number.
InChI:InChI=1/C5H11NO3/c1-4(5(8)9)6-2-3-7/h4,6-7H,2-3H2,1H3,(H,8,9)/t4-/m1/s1
125412-04-6Relevant articles and documents
N-phosphorylated amino acids as potential cytostatics
Schwieger,Unterhalt
, p. 709 - 715 (2007/10/02)
Phosphoramidic dichlorides 3 are synthesized by nucleophilic attack of methyl 2-(1-ethylenimino)-alkanoates 1 on POCl3 or by the reaction of amino acid methyl ester hydrochlorides 2 with POCl3. Subsequent treatment of 3 with ethylenimine affords the TEPA-analogs 4, and with 3-(1-ethylenimino)-1-propanol (6) the IFOSFAMID analogous 1,3,2-oxaza-phosphorines 5, the cytostatic activity of which was tested in the P388-leukemia of the CD2F1-mouse.
