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5-bromo-3-(difluoromethyl)-2-methoxypyridine is a pyridine derivative with the molecular formula C6H4BrF2NO. It features a bromine atom at the 5 position, a difluoromethyl group at the 3 position, and a methoxy group at the 2 position. This chemical compound is recognized for its versatility as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds, making it a valuable intermediate in various chemical reactions due to its unique structure.

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  • 1254123-51-7 Structure
  • Basic information

    1. Product Name: 5-Bromo-3-(difluoromethyl)-2-methoxypyridine
    2. Synonyms: 5-Bromo-3-(difluoromethyl)-2-methoxypyridine
    3. CAS NO:1254123-51-7
    4. Molecular Formula: C7H6NOF2Br
    5. Molecular Weight: 238.04
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1254123-51-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 5-Bromo-3-(difluoromethyl)-2-methoxypyridine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-Bromo-3-(difluoromethyl)-2-methoxypyridine(1254123-51-7)
    11. EPA Substance Registry System: 5-Bromo-3-(difluoromethyl)-2-methoxypyridine(1254123-51-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1254123-51-7(Hazardous Substances Data)

1254123-51-7 Usage

Uses

Used in Pharmaceutical Industry:
5-bromo-3-(difluoromethyl)-2-methoxypyridine is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic applications. Its unique structural features allow for the creation of diverse chemical entities that can be optimized for specific medicinal properties.
Used in Agrochemical Industry:
In the agrochemical sector, 5-bromo-3-(difluoromethyl)-2-methoxypyridine is utilized as a precursor in the production of agrochemicals, such as pesticides and herbicides. Its chemical properties enable the design of compounds that can effectively control, repel, or kill pests and weeds, thereby enhancing crop protection and yield.
Used in Organic Synthesis:
5-bromo-3-(difluoromethyl)-2-methoxypyridine is employed as a versatile building block in organic synthesis for the creation of a wide range of organic compounds. Its reactivity and structural attributes facilitate its use in the formation of complex molecules for various applications, including materials science, specialty chemicals, and more.
Used in Drug Discovery:
5-bromo-3-(difluoromethyl)-2-methoxypyridine is used as a starting material in drug discovery processes, where its unique structure can be leveraged to design and develop new pharmaceutical agents. 5-bromo-3-(difluoromethyl)-2-methoxypyridine's potential to be modified and combined with other molecules makes it an attractive candidate for the exploration of novel therapeutic agents.
Used in Chemical Research:
5-bromo-3-(difluoromethyl)-2-methoxypyridine is also utilized in chemical research to study reaction mechanisms, explore new synthetic routes, and understand the properties of pyridine derivatives. Its unique substitution pattern provides a platform for investigating the effects of different functional groups on chemical behavior and reactivity.

Check Digit Verification of cas no

The CAS Registry Mumber 1254123-51-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,4,1,2 and 3 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1254123-51:
(9*1)+(8*2)+(7*5)+(6*4)+(5*1)+(4*2)+(3*3)+(2*5)+(1*1)=117
117 % 10 = 7
So 1254123-51-7 is a valid CAS Registry Number.

1254123-51-7Downstream Products

1254123-51-7Relevant articles and documents

INHIBITING HUMAN INTEGRIN α4β7

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Page/Page column 239; 287; 288, (2021/04/23)

Disclosed are small molecule antagonists of human α4β7 integrin, and methods of using them to treat a number of diseases and conditions.

ANTAGONISTS OF HUMAN INTEGRIN (ALPHA4)(BETA7)

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Paragraph 0228; 1120; 1121, (2019/10/29)

Disclosed are small molecule antagonists of α4β7 integrin, and methods of using them to treat a number of specific diseases or conditions.

Compounds and their use as BACE inhibitors

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Page/Page column 18, (2012/07/13)

The present invention relates to novel compounds of formula (I) and their pharmaceutical compositions. In addition, the present invention relates to therapeutic methods for the treatment and/or prevention of Aβ-related pathologies such as Down's syndrome, β-amyloid angiopathy such as but not limited to cerebral amyloid angiopathy or hereditary cerebral hemorrhage, disorders associated with cognitive impairment such as but not limited to MCI (“mild cognitive impairment”), Alzheimer's disease, memory loss, attention deficit symptoms associated with Alzheimer's disease, neurodegeneration associated with diseases such as Alzheimer's disease or dementia including dementia of mixed vascular and degenerative origin, pre-senile dementia, senile dementia and dementia associated with Parkinson's disease, progressive supranuclear palsy or cortical basal degeneration.

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