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Methyl 6-chloro-5-cyanopicolinate is a chemical compound with the formula C7H5ClN2O2, derived from picolinic acid. It is characterized by its strong cyanide group and chlorine substituent, making it a versatile building block for the synthesis of complex organic compounds. Methyl 6-chloro-5-cyanopicolinate is known for its potential biological activity and is commonly used in the pharmaceutical and agricultural industries as an intermediate in the synthesis of various pharmaceutical products and agrochemicals.

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  • 1254163-81-9 Structure
  • Basic information

    1. Product Name: Methyl 6-chloro-5-cyanopicolinate
    2. Synonyms: Methyl 6-chloro-5-cyanopicolinate;methyl 6-chloro-5-cyanopyridine-2-carboxylate
    3. CAS NO:1254163-81-9
    4. Molecular Formula: C8H5ClN2O2
    5. Molecular Weight: 196.5905
    6. EINECS: -0
    7. Product Categories: N/A
    8. Mol File: 1254163-81-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: Methyl 6-chloro-5-cyanopicolinate(CAS DataBase Reference)
    10. NIST Chemistry Reference: Methyl 6-chloro-5-cyanopicolinate(1254163-81-9)
    11. EPA Substance Registry System: Methyl 6-chloro-5-cyanopicolinate(1254163-81-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1254163-81-9(Hazardous Substances Data)

1254163-81-9 Usage

Uses

Used in Pharmaceutical Industry:
Methyl 6-chloro-5-cyanopicolinate is used as an intermediate in the synthesis of various pharmaceutical products for its potential biological activity. It contributes to the development of new drugs by providing a versatile building block for complex organic compound synthesis.
Used in Agricultural Industry:
Methyl 6-chloro-5-cyanopicolinate is used as an intermediate in the synthesis of agrochemicals, particularly for its potential use in developing new pesticides or other agricultural chemicals. Its strong cyanide group and chlorine substituent make it a valuable component in creating effective and targeted agrochemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 1254163-81-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,4,1,6 and 3 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1254163-81:
(9*1)+(8*2)+(7*5)+(6*4)+(5*1)+(4*6)+(3*3)+(2*8)+(1*1)=139
139 % 10 = 9
So 1254163-81-9 is a valid CAS Registry Number.

1254163-81-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 6-chloro-5-cyanopyridine-2-carboxylate

1.2 Other means of identification

Product number -
Other names Methyl 6-chloro-5-cyanopicolinate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1254163-81-9 SDS

1254163-81-9Downstream Products

1254163-81-9Relevant articles and documents

IMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF CYCLIN DEPENDENT KINASES

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Page/Page column 256-257, (2010/11/17)

The invention provides compounds of the formula (I): and salts, tautomers, solvates and N-oxides thereof; wherein Q is CH or N; X is N, N+-O- or CR3; Y is N, N+-O- or CR3a; R1 and R2 are independently selected from hydrogen and various substituents as defined in the claims; or R1 and R2 together with the atoms to which they are attached, link to form an optionally substituted carbocyclic or heterocyclic aromatic or non-aromatic ring of 4 to 7 members; R3 is selected from hydrogen and various substituents; and R3a is selected from hydrogen and various substituents as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds. The compounds of formula (I) have activity as inhibitors of CDK kinases and are useful in the treatment of inter alia proliferative diseases such as cancers.

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