125418-72-6

Basic information

• Product Name: Hydroxyethylanisol
• Synonyms: Hydroxyethylanisol;2-(4-Methoxy-3-nitroanilino)ethan-1-ol, N-(2-Hydroxyethyl)-4-methoxy-3-nitroaniline;2-[(4-Methoxy-3-nitrophenyl)amino]ethan-1-ol
• CAS NO: 125418-72-6
• Molecular Formula: C9H12N2O4
• Molecular Weight: 212.2
• Mol File: 125418-72-6.mol

Chemical Properties

• Boiling Point: 420.2°C at 760 mmHg
• Flash Point: 207.9°C
• Appearance: /
• Density: 1.336g/cm³
• Vapor Pressure: 8.19E-08mmHg at 25°C
• Refractive Index: 1.612
• CAS DataBase Reference: Hydroxyethylanisol(CAS DataBase Reference)
• NIST Chemistry Reference: Hydroxyethylanisol(125418-72-6)
• EPA Substance Registry System: Hydroxyethylanisol(125418-72-6)

Safety Data

• Hazardous Substances Data: 125418-72-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H12N2O4/c1-15-9-3-2-7(10-4-5-12)6-8(9)11(13)14/h2-3,6,10,12H,4-5H2,1H3

Upstream product

• 952581-88-3 3-(4-Methoxy-3-nitrophenyl)-1,3-oxazolidine-2-one 
• 577-72-0 4-methoxy-3-nitroaniline 
• 627-11-2 2-Chloroethyl chloroformate 
• 364-76-1 4-Fluoro-3-nitroaniline 

Relevant articles and documents

2-amino-4 - (β-hydroxyethyl amino) anisole and its sulphate preparation method

The invention relates to 2-amino-4-(beta-hydroxyethylamino) methoxybenzene and a preparation method of 2-amino-4-(beta-hydroxyethylamino) methoxybenzene sulfate. The preparation method comprises the steps as follows: 3-nitro-para-fluoroaniline is adopted as a raw material and subjected to nucleophilic substitution to produce 3-nitro-4-anisidine; 3-nitro-4-anisidine and chloroethyl chloroformate are subjected to condensation to synthesize 2-nitro-4-(beta-hydroxyethylamino) methoxybenzene with a hydrolysis and decarboxylation one-pot method; and 2-nitro-4-(beta-hydroxyethylamino) methoxybenzene has the hydrogenation reduction reaction to obtain a target product 2-amino-4-(beta-hydroxyethylamino) methoxybenzene which reacts with sulfate salt to obtain 2-amino-4-(beta-hydroxyethylamino) methoxybenzene sulfate. 2-amino-4-(beta-hydroxyethylamino) methoxybenzene and the preparation method of 2-amino-4-(beta-hydroxyethylamino) methoxybenzene sulfate have the advantages of high product quality, good yield, stable technology, small emission of three wastes, low cost, good economic efficiency and the like, and synthesis materials are easy to obtain.

New process for the preparation of 4-hydroxalkylamino-2-nitro-anisoles

A process for the preparation of 4-hydroxyalkylamino-2-nitro-anisoles of the general formula (I) wherein m is 2 or 3; by reaction of a 4-halogeno-3-nitro-aniline of formula (II) with a chloroalkyl-chloroformate of formula (III), alkaline ring closure of t

Process for the preparation of hydroxyalkylaminonitrobenzene derivatives

The present invention relates to a process for the preparation of compounds of the general formula I STR1 by reaction of compounds of the general formula II STR2 with compounds of the general formula III STR3 in inert aprotic solvents in the presence of a base and subsequent rearrangement of the resulting intermediate compound with an alkali metal hydroxide, characterized in that the intermediate compound is not isolated.