A versatile one-pot multicomponent synthesis of novel quinazolinon-2-yl- tetrasubstituted thiophenes
Here, we report a versatile multicomponent synthesis of novel quinazolinon-2-yl-tetrasubstituted thiophenes by a one-pot reaction using different alkyl-3-aminobutenoates, isothiocyanates and 2-halomethyl quinazolinones in good to excellent yields. The reaction probably proceeds by an intramolecular 5-exo-trig cyclisation.
Jalani, Hitesh B.,Kaila, Jitendra C.,Baraiya, Arshi B.,Pandya, Amit N.,Sudarsanam,Vasu, Kamala K.