125736-01-8 Usage
Uses
Used in Organic Synthesis:
Tert-butyl 2-(1-[tert-butyl(dimethyl)silyl]oxyethenyl)-9-azabicyclo[4.2.1]nonane-9-carboxylate is employed as a key intermediate in organic synthesis, particularly for the preparation of complex organic molecules. Its unique structure and reactivity make it a versatile component in the synthesis of various compounds.
Used in Pharmaceutical Drug Development:
In the pharmaceutical industry, tert-butyl 2-(1-[tert-butyl(dimethyl)silyl]oxyethenyl)-9-azabicyclo[4.2.1]nonane-9-carboxylate is used as a potential precursor in the development of new drugs. Its structural features and chemical properties allow for the exploration of its potential therapeutic applications, making it a promising candidate for further research and development.
Used in Medicinal Chemistry:
Tert-butyl 2-(1-[tert-butyl(dimethyl)silyl]oxyethenyl)-9-azabicyclo[4.2.1]nonane-9-carboxylate is utilized as a building block in medicinal chemistry for the synthesis of bioactive molecules. Its presence in the molecular structure can influence the pharmacological properties of the final product, offering a wide range of possibilities for the design of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 125736-01-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,7,3 and 6 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 125736-01:
(8*1)+(7*2)+(6*5)+(5*7)+(4*3)+(3*6)+(2*0)+(1*1)=118
118 % 10 = 8
So 125736-01-8 is a valid CAS Registry Number.
125736-01-8Relevant articles and documents
Chirospecific Syntheses of Nitrogen and Side-Chain Modified Anatoxin Analogues. Synthesis of (1R)-Anatoxinal and (1R)-Anatoxinic Acid Derivatives
Howard, Michael H.,Sardina, F. Javier,Rapoport, Henry
, p. 2829 - 2838 (2007/10/02)
A straightforward and good yielding route to side-chain analogues of the potent neurotoxin and neurotransmitter (+)-anatoxin (1) has been developed.Peroxy acid oxidation of the (silyloxy)butadiene 43 derived from readily synthesized, optically pure (1R)-t-BOC-anatoxin (42) affords silyloxy ketone 44.Fluorolysis of 44 followed by oxidative cleavage of the resultant α-hydroxy ketone 45 gives a mixture of α,β-unsaturated acid 46 and ester 41 in 57percent combined yield.Other approaches to these compounds, based on literature precedent, failed. (1R)-t-BOC-anatoxinic acid (46) then serves as educt for the synthesis of a wide variety of anatoxin derivatives with modified side-chain functionality.These analogues, designed to serve as probes of the antagonist binding site of the nicotinic acetylcholine receptor, include alcohol, aldehyde, amide, hydroxamate, and oxime ether functional groups.