125879-68-7Relevant articles and documents
A simple, highly regioselective and efficient reaction of indole with epoxides under solvent-free conditions
Azizi, Najmedin,Mehrazma, Shokopheh,Saidi, Mohammad R.
, p. 800 - 803 (2006)
Lithium perchlorate has been found to be an inexpensive and efficient catalyst for the ring opening of epoxides by indole and N-methylindole, which provides an environmentally friendly method for the synthesis of substituted indoles. A complete regioselec
Iron-containing ionic liquid as an efficient and recyclable catalyst for the synthesis of C3-substituted indole derivatives
Gu, Ying-Chun,Hu, Ren-Ming,Li, Ming-Ming,Xu, Da-Zhen
, (2019)
A facile and efficient protocol for the synthesis of C3-substituted indole derivatives has been developed under mild condition. The iron-containing ionic liquid, 1-(2-hydroxyethyl)-1,4-diazabicyclo[2.2.2] octanylium tetrachloroferrate ([Dabco-C2/sub
Friedel-Crafts alkylation of indoles with epoxides catalyzed by nanocrystalline titanium(IV) oxide
Kantam, M. Lakshmi,Laha, Soumi,Yadav, Jagjit,Sreedhar
, p. 6213 - 6216 (2006)
Friedel-Crafts alkylation of indoles with epoxides to afford 3-alkyl indole derivatives at room temperature with moderate to good yields and high regioselectivity using nanocrystalline titanium(IV) oxide catalyst is described.
A facile synthesis of alkylated nitrogen heterocycles catalysed by 3D mesoporous aluminosilicates with cage type pores in aqueous medium
Chakravarti, Rajashree,Kalita, Pranjal,Selvan, S. Tamil,Oveisi, Hamid,Balasubramanian,Kantam, M. Lakshmi,Vinu, Ajayan
, p. 49 - 53 (2010)
Friedel-Crafts alkylation of nitrogen heterocycles such as indoles and pyrroles with epoxides has been efficiently carried out using cage-type mesoporous aluminosilicates as recyclable catalysts in water under environmentally benign and mild conditions.
MIL-101(Fe) as an active heterogeneous solid acid catalyst for the regioselective ring opening of epoxides by indoles
Nagarjun, Nagarathinam,Concepcion, Patricia,Dhakshinamoorthy, Amarajothi
, (2019/12/09)
Ring opening of an epoxide by a nucleophile is considered as one of the viable strategies to prepare biologically active molecules using homogeneous or heterogeneous Lewis acid catalysts. Very often, the ring opening of epoxide was performed with oxygen,
Regio- and enantioselective Friedel-Crafts reactions of indoles to epoxides catalyzed by graphene oxide: A green approach
Acocella, Maria Rosaria,Mauro, Marco,Guerra, Gaetano
, p. 3279 - 3283 (2015/02/03)
Graphene oxide efficiently promotes high regio- and enantioselective ring opening reactions of aromatic epoxides by indoles addition, in solvent- and metal-free conditions. The Friedel-Crafts products were obtained with enantioselectivity up to 99% ee. Th
Magnetic nano Fe3O4 and CuFe2O4 as heterogeneous catalysts: A green method for the stereo- and regioselective reactions of epoxides with indoles/pyrroles
Parella, Ramarao,Naveen,Babu, Srinivasarao Arulananda
, p. 118 - 121 (2013/01/15)
In this paper, we report a new solvent-free catalytic method using the magnetic nano Fe3O4 and CuFe2O4 as competent heterogeneous catalysts for the stereo- and regioselective reactions of epoxides with indoles/p
Friedel-Crafts Alkylation of Nitrogen Heterocycles Using [Bmim][OTf] as a Catalyst and Reaction Medium
Kantam, M. Lakshmi,Chakravarti, Rajashree,Sreedhar,Bhargava, Suresh
experimental part, p. 1449 - 1454 (2009/04/07)
Friedel-Crafts alkylation of nitrogen heterocycles, such as indoles and pyrroles, can be carried out in ionic liquids under mild conditions to afford the corresponding alkylated product in moderate to good yields.
High-pressure organic chemistry. 19. High-pressure-promoted, silica gel-catalyzed reaction of epoxides with nitrogen heterocycles
Kotsuki, Hiyoshizo,Hayashida, Katsunori,Shimanouchi, Tomoyasu,Nishizawa, Hitoshi
, p. 984 - 990 (2007/10/03)
The reaction of epoxides with nitrogen heterocycles such as indoles, pyrroles, imidazoles, and pyrazoles was studied under both high-pressure and silica gel-catalyzed conditions. Whereas it has been reported that the treatment of indole with styrene oxide