Biarylimidazoles as inhibitors of microsomal prostaglandin E2 synthase-1
Microsomal prostaglandin E2 synthase (mPGES-1) represents a potential target for novel analgesic and anti-inflammatory agents. High-throughput screening identified several leads of mPGES-1 inhibitors which were further optimized for potency and
Wu, Tom Y.H.,Juteau, Hélne,Ducharme, Yves,Friesen, Richard W.,Guiral, Sébastien,Dufresne, Lynn,Poirier, Hugo,Salem, Myriam,Riendeau, Denis,Mancini, Joseph,Brideau, Christine
scheme or table
p. 6978 - 6982
(2011/02/25)
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