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126101-07-3

2,5-dioxotetrahydro-1H-pyrrolo[1,2-a]imidazole-7a(5H)-carboxylic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 126101-07-3 Structure

  • Basic information

    1. Product Name: 2,5-dioxotetrahydro-1H-pyrrolo[1,2-a]imidazole-7a(5H)-carboxylic acid
    2. Synonyms: 1H-pyrrolo[1,2-a]imidazole-7a(5H)-carboxylic acid, tetrahydro-2,5-dioxo-
    3. CAS NO:126101-07-3
    4. Molecular Formula: C7H8N2O4
    5. Molecular Weight: 184.1494
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 126101-07-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 614.2°C at 760 mmHg
    3. Flash Point: 325.3°C
    4. Appearance: N/A
    5. Density: 1.66g/cm3
    6. Vapor Pressure: 1.14E-16mmHg at 25°C
    7. Refractive Index: 1.636
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 2,5-dioxotetrahydro-1H-pyrrolo[1,2-a]imidazole-7a(5H)-carboxylic acid(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2,5-dioxotetrahydro-1H-pyrrolo[1,2-a]imidazole-7a(5H)-carboxylic acid(126101-07-3)
    12. EPA Substance Registry System: 2,5-dioxotetrahydro-1H-pyrrolo[1,2-a]imidazole-7a(5H)-carboxylic acid(126101-07-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 126101-07-3(Hazardous Substances Data)

126101-07-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 126101-07-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,1,0 and 1 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 126101-07:
(8*1)+(7*2)+(6*6)+(5*1)+(4*0)+(3*1)+(2*0)+(1*7)=73
73 % 10 = 3
So 126101-07-3 is a valid CAS Registry Number.

126101-07-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,5-dioxo-1,3,6,7-tetrahydropyrrolo[1,2-a]imidazole-7a-carboxylic acid

1.2 Other means of identification

Product number -
Other names 2,5-Dioxohexahydro-1H-pyrrolo(1,2-a)imidazole-7a-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:126101-07-3 SDS

126101-07-3Relevant articles and documents

Synthesis and pharmacological activity of a series of dihydro-1H- pyrrolo[1,2-a]imidazole-2,5(3H,6H)-diones, a novel class of potent cognition enhancers

Pinza,Farina,Cerri,Pfeiffer,Riccaboni,Banfi,Biagetti,Pozzi,Magnani,Dorigotti

, p. 4214 - 4220 (2007/10/02)

A series of dihydro-1H-pyrrolo[1,2-a]imidazole-2,5(3H,6H)-diones were synthesized. These bicylic derivatives contain both the 2-pyrrolidinone and 4-imidazolidinone nuclei, already recognized as important for cognition enhancing activity. In addition, these structures maintain the backbone of piracetam and oxiracetam with the acetamide side chain restricted in a folded conformation. Their ability to reverse scopolamine-induced amnesia was assessed in a one trial, step-through, passive avoidance paradigm. The main features observed are a potent antiamnestic activity after ip administration (minimal effective dose being between 0.3 and 1 mg/kg ip for most compounds), the presence of a bell-shaped dose-response curve and, generally, a reduction of biological activity after po administration. However, the unsubstituted compound (15, dimiracetam) shows no evidence of a bell-shaped dose-response curve and completely retains activity when given orally, being 10-30 times more potent than the reference drug oxiracetam.

Psychotropic perhydroazacycloalka [1,2-A] imidazole derivatives

-

, (2008/06/13)

Imidazole derivatives are described which are useful in restoring learning and treating memory difficulties. A compound of the invention is 2,5-dioxohexahydro-1H-pyrrolo[1,2-a]imidazole.

Condensed imidazole derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them.

-

, (2008/06/13)

Compounds of structure (I) in which, R1 is hydrogen, C1 4alkyl, CHR6CONHR7 or CHR6COOR7 in which R6 and R7 are each hydrogen or C1 4alkyl; R2 is hydrogen, C1 5alkyl or a residue R2 of an amino acid R2 CH(NH2)COOH; R3 is hydrogen, C1 4alkyl, CONH2 or CO2R8 in which R8 is hydrogen or C1 4alkyl; and n is 2, 3 or 4, processes for their preparation, intermediates useful in their preparation, pharmaceutical composition containing them and their use in therapy as nootropic agents.

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