126144-69-2

Basic information

• Product Name: 1-Azabicyclo[3.3.1]nonane-2,6-dione
• Synonyms: 1-Azabicyclo[3.3.1]nonane-2,6-dione
• CAS NO: 126144-69-2
• Molecular Formula: C8H11NO2
• Molecular Weight: 153.17844
• Mol File: 126144-69-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Azabicyclo[3.3.1]nonane-2,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Azabicyclo[3.3.1]nonane-2,6-dione(126144-69-2)
• EPA Substance Registry System: 1-Azabicyclo[3.3.1]nonane-2,6-dione(126144-69-2)

Safety Data

• Hazardous Substances Data: 126144-69-2(Hazardous Substances Data)

Usage

Type of Compound

Heterocyclic compound

Bicyclic Structure

Contains two nitrogen atoms

Classification

Cyclic imide and lactam

Usage

Organic synthesis and medicinal chemistry

Biological Activities

Antiproliferative and antifungal properties

Applications

Synthesis of alkaloids and complex organic compounds

Structure

Unique bicyclic structure with two nitrogen atoms

Importance

Valuable building block for pharmaceuticals and functional materials development

Upstream product

• 126144-70-5 3-(2-carboxyethyl)-4-piperidone 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 16675-58-4 1-Benzyl-4-(1-pyrrolidinyl)-1,2,3,6-tetrahydro-pyridine 
• 126144-72-7 3-(2-benzyloxycarbonylethyl)-N-benzyl-4-piperidone 

Relevant articles and documents

Conformational Study of Bridgehead Lactams. Preparation and X-Ray Structural Analysis of 1-Azabicyclononane-2,6-dione

3-(2-carboxyethyl)-4-piperidone (5) prepared, from N-benzyl-4-piperidone and benzyl acrylate (9), was thermally cyclized in the presence of dibutyltin oxide to 1-azabicyclononane-2,6-dione (4), which possesses a bridgehead amide nitrogen.The boat-chair conformation of (4) in the solid state has been characterized by X-ray crystal structure analysis and the bridgehead amide shown to be appreciably distorted from planarity, with N(1) displaced by 0.37 Angstroem from the plane of C(2), C(8), and C(9).Crystallographic data are a=6.214(4), b=6.845(5), c=17.850(8) Angstroem, Z=4, space group P21cn.X-Ray intensity measurements were made on a four-circle diffractometer and least-squares adjustment of the atomic parameters converged at R=0.038 for 1004 reflections.