Efficient synthesis of a 7-azabicyclo[2.2.1]heptane based GlyT1 uptake inhibitor
An efficient synthetic route based on generation and subsequent electrophilic reaction of a Boc-protected azabicyclo[2.2.1]heptane anion to prepare a potent GlyT1 uptake inhibitor (1) is described.
Xiong, Hui,Frietze, William,Andisik, Donald W.,Ernst, Glen E.,Palmer, William E.,Hinkley, Lindsay,Varnes, Jeffrey G.,Albert, Jeffrey S.,Veale, Chris A.
experimental part
p. 6741 - 6744
(2011/02/25)
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