A 4-Dimethylaminopyridine-Catalyzed Aminolysis of β-Ketoesters. Formation of β-Ketoamides
Alkyl 3-oxoalkanoates (β-ketoesters) react with amines in the presence of a catalytic amount of 4-dimethylaminopyridine (DMAP) under mild conditions to form 3-oxoalkanamides (β-ketoamides) in good yields.
Cossy, Janine,Thellend, Annie
p. 753 - 755
(2007/10/02)
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