cas 126554-50-5, (6aR,9R,10aR)-7-allyl-N<sup>9</sup>-[3-(dimethylamino)propyl]-N<sup>4</sup>-ethyl-N<sup>9</sup>-(ethylcarbamoyl)-6a,7,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-4,9(6H)-dicarboxamide | Articles data ｜lookchem

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126554-50-5

Articles about 126554-50-5Total 2 be found

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Synthesis of European pharmacopoeial impurities A, B, C, and D of cabergoline
For the use of analytics, European pharmacopoeial impurities A, B, C, and D of cabergoline were synthesized. Ergocryptine was chosen as a starting material and synthesis was accomplished via two approaches, different in length and stereochemical outcome. A longer, indirect approach was realized through otherwise problematic oxidations of the 9,10-dihidrolysergol derivative, to the corresponding aldehyde and carboxylic acid. This was achieved by the use of activated DMSO and a Pinnick oxidation sequence. All four synthesized impurities are used as analytical standards in cabergoline manufacturing processes.
Wagger, Jernej,Pozes, Aljaz,Pozgan, Franc
p. 23146 - 23156
(2013)
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Synthesis and nidation inhibitory activity of a new class of ergoline derivatives
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Brambilla,Disalle,Briatico,Mantegani,Temperilli
p. 421 - 426
(2007/10/02)

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Chemical Properties

Melting Point: 125-127 °C(Solv: isopropyl ether (108-20-3))
Density: 1.23±0.1 g/cm3(Predicted)

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