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2-(2-(3-chloropropyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a complex chemical compound characterized by a cyclopropyl group with a chloropropyl attached to it, along with four methyl groups and a dioxaborolane ring. 2-(2-(3-chloropropyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is known for its unique structure and properties, making it a valuable building block in organic synthesis and pharmaceutical research.

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  • 2-(2-(3-CHLOROPROPYL)CYCLOPROPYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE

    Cas No: 126726-63-4

  • USD $ 1.9-2.9 / Gram

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  • 126726-63-4 Structure
  • Basic information

    1. Product Name: 2-(2-(3-chloropropyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
    2. Synonyms: 2-(2-(3-chloropropyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;trans-2-[2-(3-Chloropropyl)cyclopropyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;trans-2-[2-(3-Chloropropyl)cyclopropyl]boronic acid pinacol ester;2-[2-(3-Chloropropyl)cyclopropyl]boronic acid pinacol ester
    3. CAS NO:126726-63-4
    4. Molecular Formula: C12H22BClO2
    5. Molecular Weight: 244.56588
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 126726-63-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 279℃
    3. Flash Point: 123℃
    4. Appearance: /
    5. Density: 1.03
    6. Vapor Pressure: 0.007mmHg at 25°C
    7. Refractive Index: 1.462
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 2-(2-(3-chloropropyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-(2-(3-chloropropyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(126726-63-4)
    12. EPA Substance Registry System: 2-(2-(3-chloropropyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(126726-63-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 126726-63-4(Hazardous Substances Data)

126726-63-4 Usage

Uses

Used in Organic Synthesis:
2-(2-(3-chloropropyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is used as a building block in organic synthesis for creating more complex compounds. Its unique structure allows for the formation of various organic molecules through cross-coupling reactions.
Used in Pharmaceutical Research:
In pharmaceutical research, 2-(2-(3-chloropropyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is utilized as a reagent in cross-coupling reactions, which are crucial for the production of a wide range of organic molecules with potential pharmaceutical applications.
Used in Agriculture:
2-(2-(3-chloropropyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane has potential applications in agriculture due to its unique structure and properties, which can be harnessed for the development of new agrochemicals and pesticides.
Used in Materials Science:
In the field of materials science, 2-(2-(3-chloropropyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane can be employed for the development of novel materials with specific properties, such as improved stability or reactivity.
Used in Biotechnology:
2-(2-(3-chloropropyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane also has potential applications in biotechnology, where its unique structure and properties can be utilized for the design and synthesis of new bioactive compounds or as components in biocatalytic processes.

Check Digit Verification of cas no

The CAS Registry Mumber 126726-63-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,7,2 and 6 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 126726-63:
(8*1)+(7*2)+(6*6)+(5*7)+(4*2)+(3*6)+(2*6)+(1*3)=134
134 % 10 = 4
So 126726-63-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H22BClO2/c1-11(2)12(3,4)16-13(15-11)10-8-9(10)6-5-7-14/h9-10H,5-8H2,1-4H3

126726-63-4Relevant articles and documents

Multikilogram-scale synthesis of a chiral cyclopropanol and an investigation of the safe use of lithium acetylide-ethylene diamine complex

Bassan, Ephraim M.,Baxter, Carl A.,Beutner, Gregory L.,Emerson, Khateeta M.,Fleitz, Fred J.,Johnson, Simon,Keen, Stephen,Kim, Mary M.,Kuethe, Jeffrey T.,Leonard, William R.,Mullens, Peter R.,Muzzio, Daniel J.,Roberge, Christopher,Yasuda, Nobuyoshi

, p. 87 - 95 (2012)

A six-step route starting from a readily available vinyl boronate was identified to produce an enantioenriched cyclopropanol in an overall 16% yield. Key steps involve the use of lithium acetylide-ethylene diamine complex 5 and an enzymatic resolution of a racemic cyclopropanol acetate. Process safety considerations surrounding the use of 5 were examined, and an improved procedure is described which was safely demonstrated at multikilogram scale.

Process and intermediates for preparing macrolactams

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Page/Page column 30; 31, (2016/02/18)

The present invention includes compounds useful as intermediates in the preparation of macrolactams, methods for preparing the intermediates, and methods for preparing macrolactams from the intermediates. One use of the methods and intermediates described herein is in the production of macrolactam compounds able to inhibit HCV NS3 protease activity. HCV NS3 inhibitory compounds have therapeutic and research applications.

Inhibitors of nedd8-activating enzyme

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Paragraph 0165, (2014/08/20)

The invention relates to an administration unit comprising crystalline form I of {(1 S,2S,4R)-4-[(6-{[(1R,2S)-5-chloro-2methoxy-2,3-dihydro-1H-inden-1-yl]amino}pyrimidin-4-yl)oxy]-2-hydroxycyclopentyl}methyl sulfamate (I-216) hydrochloride salt and to a packaging comprising the administration unit according to the invention.

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