126737-42-6

Basic information

• Product Name: Acetylsventenic acid
• Synonyms: Acetylsventenic acid;(4beta,7beta)-7-(Acetyloxy)-kaur-16-en-18-oic acid
• CAS NO: 126737-42-6
• Molecular Formula: C22H32O4
• Molecular Weight: 360.48708
• Mol File: 126737-42-6.mol

Chemical Properties

• Boiling Point: 475.1±45.0 °C(Predicted)
• Appearance: /
• Density: 1.15±0.1 g/cm3(Predicted)
• PKA: 4.55±0.60(Predicted)
• CAS DataBase Reference: Acetylsventenic acid(CAS DataBase Reference)
• NIST Chemistry Reference: Acetylsventenic acid(126737-42-6)
• EPA Substance Registry System: Acetylsventenic acid(126737-42-6)

Safety Data

• Hazardous Substances Data: 126737-42-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Acetylsalicylic acid is used as a pain reliever and fever reducer for its ability to inhibit the production of prostaglandins, which are responsible for inflammation and pain.
Used in Cardiovascular Health:
Acetylsalicylic acid is used as a blood thinner to help prevent blood clots, thereby reducing the risk of heart attacks and strokes.
Used in Chemical Production:
Acetylsalicylic acid is used as a raw material in the production of dyes, fragrances, and plastics, contributing to the versatility of its applications across various industries.

Upstream product

• 43161-43-9 7β-acetoxy-18-hydroxy-ent-kaur-16-ene 
• 43161-40-6 7β-acetoxy-ent-kaur-16-ene 
• 21435-01-8 7β-hydroxy-(-)-kaur-16-en-19-oic acid 
• 108-24-7 acetic anhydride 
• 43161-43-9 Epicandicandiol 7β-monoacetate 

Downstream Products

• 18493-13-5 Sventenic acid 

Relevant articles and documents

Biotransformation of ent-kaur-16-ene and ent-trachylobane 7β-acetoxy derivatives by the fungus Gibberella fujikuroi (Fusarium fujikuroi)

Candol A (7β-hydroxy-ent-kaur-16-ene) (6) is efficiently transformed by Gibberella fujikuroi into the gibberellin plant hormones. In this work, the biotransformation of its acetate by this fungus has led to the formation of 7β-acetoxy-ent-kaur-16-en-19-oic acid (3), whose corresponding alcohol is a short-lived intermediate in the biosynthesis of gibberellins and seco-ring ent-kaurenoids in this fungus. Further biotransformation of this compound led to the hydroxylation of the 3β-positions to give 7β-acetoxy-3β- hydroxy-ent-kaur-16-en-19-oic acid (14), followed by a 2β- or 18-hydroxylation of this metabolite. The incubation of epicandicandiol 7β-monoacetate (7β-acetoxy-18-hydroxy-ent-kaur-16-ene) (10) produces also the 19-hydroxylation to form the 18,19 diol (20), which is oxidized to give the corresponding C-18 or C-19 acids. These results indicated that the presence of a 7β-acetoxy group does not inhibit the fungal oxidation of C-19 in 7β-acetoxy-ent-kaur-16-ene, but avoids the ring B contraction that leads to the gibberellins and the 6β-hydroxylation necessary for the formation of seco-ring B ent-kaurenoids. The biotransformation of 7β-acetoxy-ent- trachylobane (trachinol acetate) (27) only led to the formation of 7β-acetoxy-18-hydroxy-ent-trachylobane (33).

DITERPENES FROM SIDERITIS SVENTENII AND S. CYSTOSIPHON

The new diterpenes, 7β-monoacetate of episinfernal, 7β-monoacetate of sideritriol, and sventenic acid, have been isolated from Sideritis sventenii.From S. cystosiphon, three new diterpenic esters, the 7β-acetate,18-palmitate of epicandicandiol, the 18-acetate of epicandicandiol, and the 7β,17-diacetate of sideritriol, have been obtained.

Didymooblongin, a New Kaurenoid Diterpene from Didymocarpus oblonga Wall.

Didymooblongin (III), a new kaurenoid diterpene isolated from the whole plant of Didymocarpus oblonga, has been formulated as 7β-hydroxy-(-)-16-kaurene-19-oic acid (III) on the basis of spectral and chemical evidences.