- Pyrrolidine and related derivatives useful as PR modulators
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Compounds of the following structure are described: wherein R1-R6, R11, R12, m, V, X, Y, Z and Q are described herein, or a pharmaceutically acceptable salt, tautomer, metabolite or prodrug thereof. These compou
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Page/Page column 15-16
(2010/11/30)
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- Highly enantioselective alkylation of glycine methyl and ethyl ester derivatives under phase-transfer conditions: Its synthetic advantage
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Phase-transfer alkylation of the benzophenone Schiff base of glycine methyl or ethyl ester (2) was found to be catalyzed by 3,4,5-F 3-C6H2-NAS-Br [(S,S)-1] with high efficiency and excellent enantioselectivity. This procedure allows facile derivatization of the resulting alkylation products to other synthetically useful chiral building blocks.
- Ooi, Takashi,Uematsu, Yukitaka,Maruoka, Keiji
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p. 1675 - 1678
(2007/10/03)
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- UNUSUAL N-ACYLATION OF GLYCINE SCHIFF BASES. A SIMPLE APPROACH TO 3,3-DIPHENYLAZIRIDINE-2-CARBOXYLATES
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Treatment of azaallyl anions, generated from glycine Schiff bases, with Ar-acyl halides furnishes N-acylaziridines via intramolecular cyclization.
- Rao, M. Narayana,Holkar, A. G.,Ayyangar, N. R.
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p. 4717 - 4720
(2007/10/02)
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