Biological evaluation of KRIBB3 analogs as a microtubule polymerization inhibitor
A series of KRIBB3 analogs were synthesized by modifying substituents at aryl moieties of KRIBB3 for examining structure-activity relationships, and their inhibitory activities on microtubule polymerization were evaluated. The presence of free phenolic hydrogens in aryl moieties of KRIBB3 analogs plays an important role in inhibition of microtubule polymerization.
Lee, Sangku,Kim, Jae Nyoung,Lee, Hyeong Kyu,Yoon, Kab Seog,Shin, Ki Deok,Kwon, Byoung-Mog,Han, Dong Cho
p. 977 - 979
(2011/03/21)
Synthesis and biological evaluation of KRIBB3 analogues on a proliferation of HCT-116 colorectal cancer cells
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Lee, Sangku,Kim, Jae Nyoung,Min, Ji Hye,Yoon, Kab Seog,Shin, Ki Deok,Kwon, Byoung-Mog,Han, Dong Cho
p. 3800 - 3802
(2011/10/02)
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