Tin (IV) chloride-promoted one-pot synthesis of novel tacrine analogues
A facile synthesis of potential acetylcholinesterase (AChE) inhibitors, the tacrine analogues 3a-p, has been accomplished by direct cyclocondensation of 1-aryl-4- cyano-5-aminopyrazole with β-ketoesters using tin(IV) chloride as catalyst. The structures o