127035-58-9Relevant articles and documents
Effect of structure on potency and selectivity in 2,6-disubstituted 4-(2-arylethenyl)phenol lipoxygenase inhibitors
Lazer,Wong,Wegner,Graham,Farina
, p. 1892 - 1898 (2007/10/02)
A series of 2,6-disubstituted 4-(2-arylethenyl)phenols with potent human neutrophil 5-lipoxygenase (5-LO) inhibiting activity (IC50s in the 10-7 M range) and weaker human platelet cyclooxygenase (CO) inhibiting activity (IC50/s
Compounds for inhibiting the biosynthesis of lipoxygenase-derived metabolites of arachidonic acid
-
, (2008/06/13)
Compounds having the formula inhibit 5-lypoxyogenase and are useful in the treatment of inflammation.