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METHYL ISOINDOLINE-5-CARBOXYLATE HYDROCHLORIDE, with the CAS number 127168-93-8, is a chemical compound that serves as a crucial reagent in the synthesis of azabicyclooctane derivatives. These derivatives are known to act as FXR inhibitors, which play a significant role in various biological processes and therapeutic applications.

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  • 127168-93-8 Structure
  • Basic information

    1. Product Name: METHYL ISOINDOLINE-5-CARBOXYLATE HYDROCHLORIDE
    2. Synonyms: METHYL ISOINDOLINE-5-CARBOXYLATE HYDROCHLORIDE;Methyl isoindoline-5-carboxylate HCl;2,3-Dihydro-1H-isoindole-5-carboxylic acid methyl ester monohydrochloride;5-(Methoxycarbonyl)isoindoline hydrochloride;Methyl 2,3-dihydro-1H-isoindole-5-carboxylate hydrochloride;Methyl 5-isoindolinecarboxylate hydrochloride (1:1);2,3-Dihydro-1H-isoindole-5-carboxylic acid methyl ester hydrochloride;2-((benzyloxy)carbonyl)isoindoline-5-carboxylic acid
    3. CAS NO:127168-93-8
    4. Molecular Formula: C10H12ClNO2
    5. Molecular Weight: 213.66100
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 127168-93-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: METHYL ISOINDOLINE-5-CARBOXYLATE HYDROCHLORIDE(CAS DataBase Reference)
    10. NIST Chemistry Reference: METHYL ISOINDOLINE-5-CARBOXYLATE HYDROCHLORIDE(127168-93-8)
    11. EPA Substance Registry System: METHYL ISOINDOLINE-5-CARBOXYLATE HYDROCHLORIDE(127168-93-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 127168-93-8(Hazardous Substances Data)

127168-93-8 Usage

Uses

Used in Pharmaceutical Industry:
METHYL ISOINDOLINE-5-CARBOXYLATE HYDROCHLORIDE is used as a reagent for the preparation of azabicyclooctane derivatives, which are essential in the development of FXR inhibitors. These inhibitors have potential applications in the treatment of various diseases and conditions, such as liver disorders and metabolic syndromes, by modulating the activity of the farnesoid X receptor (FXR).
Used in Chemical Synthesis:
In the field of chemical synthesis, METHYL ISOINDOLINE-5-CARBOXYLATE HYDROCHLORIDE is utilized as a key intermediate in the production of various compounds, including pharmaceuticals and other specialty chemicals. Its unique chemical structure allows for the creation of a wide range of molecules with diverse applications, making it a valuable asset in the chemical industry.

Check Digit Verification of cas no

The CAS Registry Mumber 127168-93-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,1,6 and 8 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 127168-93:
(8*1)+(7*2)+(6*7)+(5*1)+(4*6)+(3*8)+(2*9)+(1*3)=138
138 % 10 = 8
So 127168-93-8 is a valid CAS Registry Number.
InChI:InChI=1S/C10H11NO2.ClH/c1-13-10(12)7-2-3-8-5-11-6-9(8)4-7;/h2-4,11H,5-6H2,1H3;1H

127168-93-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name Methyl isoindoline-5-carboxylate hydrochloride

1.2 Other means of identification

Product number -
Other names methyl 2,3-dihydro-1H-isoindole-5-carboxylate,hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:127168-93-8 SDS

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