127235-62-5Relevant articles and documents
Pyrimidine intermediates
-
, (2008/06/13)
The present invention is directed to compounds of formula (I), STR1 wherein R1 is OH, NH2 ; R2 is a heteroaromatic or aromatic substituent; R3 is H, OH, F, OCH3 ; R4 is H, F, OH or an ether
5-(5-Bromothien-2-yl)-2'-deoxyuridine and 5-(5-Chlorothien-2-yl)-2'-deoxyuridine Are Equipotent to (E)-5-(2-Bromovinyl)-2'-deoxyuridine in the Inhibition of Herpes Simplex Virus Type I Replication
Wigerinck, P.,Pannecouque, C.,Snoeck, R.,Claes, P.,Clercq, E. De,Herdewijn, P.
, p. 2383 - 2389 (2007/10/02)
2'-Deoxyuridines with a five-membered heterocyclic substituent in the 5-position were synthesized by palladium-catalyzed coupling reactions of 5-iodo-2'-deoxyuridine with the activated heteroaromatics.Further modification of the compound with the 5-thien-