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2-tert-butoxyaniline is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 127517-27-5 Structure
  • Basic information

    1. Product Name: 2-tert-butoxyaniline
    2. Synonyms:
    3. CAS NO:127517-27-5
    4. Molecular Formula: C10H15NO
    5. Molecular Weight: 165.2322
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 127517-27-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 253°C at 760 mmHg
    3. Flash Point: 103.2°C
    4. Appearance: N/A
    5. Density: 0.999g/cm3
    6. Vapor Pressure: 0.0187mmHg at 25°C
    7. Refractive Index: 1.529
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 2-tert-butoxyaniline(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-tert-butoxyaniline(127517-27-5)
    12. EPA Substance Registry System: 2-tert-butoxyaniline(127517-27-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 127517-27-5(Hazardous Substances Data)

127517-27-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 127517-27-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,5,1 and 7 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 127517-27:
(8*1)+(7*2)+(6*7)+(5*5)+(4*1)+(3*7)+(2*2)+(1*7)=125
125 % 10 = 5
So 127517-27-5 is a valid CAS Registry Number.

127517-27-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[(2-Methyl-2-propanyl)oxy]aniline

1.2 Other means of identification

Product number -
Other names 2-tert-butoxy-phenylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:127517-27-5 SDS

127517-27-5Relevant articles and documents

Total Synthesis of Dictyodendrins A–F by the Gold-Catalyzed Cascade Cyclization of Conjugated Diyne with Pyrrole

Inuki, Shinsuke,Matsuda, Yuka,Matsuoka, Junpei,Miyamoto, Yoichi,Ohno, Hiroaki,Oishi, Shinya,Oka, Masahiro,Otani, Mayumi

, (2020/07/13)

The total synthesis of dictyodendrins A–F was achieved by using the gold(I)-catalyzed annulation of a conjugated diyne with N-Boc-pyrrole for direct construction of the pyrrolo[2,3-c]carbazole scaffold. Late-stage functionalization of the resulting pyrrolo[2,3-c]carbazole to introduce various substituents provided divergent access to dictyodendrins. Some dictyodendrin analogues exhibited inhibitory activities toward CDK2/CycA2 and GSK3.

Fe-Catalyzed Amination of (Hetero)Arenes with a Redox-Active Aminating Reagent under Mild Conditions

Liu, Jianzhong,Wu, Kai,Shen, Tao,Liang, Yujie,Zou, Miancheng,Zhu, Yuchao,Li, Xinwei,Li, Xinyao,Jiao, Ning

supporting information, p. 563 - 567 (2017/01/18)

A novel and efficient Fe-catalyzed direct C?H amination (NH2) of arenes is reported using a new redox-active aminating reagent. The reaction is simple, and can be performed under air, mild, and redox-neutral conditions. This protocol has a broad substrate scope and could be used in the late-stage modification of bioactive compounds. Mechanistic studies demonstrate that a radical pathway could be involved in this transformation.

Total Synthesis of Dictyodendrins by the Gold-Catalyzed Cascade Cyclization of Conjugated Diynes with Pyrroles

Matsuoka, Junpei,Matsuda, Yuka,Kawada, Yuiki,Oishi, Shinya,Ohno, Hiroaki

, p. 7444 - 7448 (2017/06/13)

In total and formal syntheses of dictyodendrins B, C, E, and F, the key step involved the direct construction of the pyrrolo[2,3-c]carbazole core by the gold-catalyzed annulation of a conjugated diyne with a pyrrole to form three bonds and two aromatic rings. The subsequent introduction of substituents at the C1 (Suzuki–Miyaura coupling), C2 (addition to an aldehyde), N3 (alkylation), and C5 positions (Ullman coupling) provided divergent access to dictyodendrins.

HETEROCYCLIC COMPOUND AND USE THEREOF

-

Paragraph 0643; 0644, (2013/06/05)

The present invention aims to provide a compound having a PDE inhibitory action and useful as a medicament for the prophylaxis or treatment of schizophrenia and the like. A compound represented by the formula (1x): wherein each symbol is as des

Total synthesis of dictyodendrins A-E

Tokuyama, Hidetoshi,Okano, Kentaro,Fujiwara, Hideto,Noji, Toshiharu,Fukuyama, Tohru

, p. 560 - 572 (2011/10/03)

A highly efficient total synthesis of dictyodendrins A-E was accomplished. The synthesis features a novel benzyne-mediated one-pot indoline formation/cross-coupling sequence for the construction of a highly substituted key indoline intermediate. Peripheral substituents were introduced onto this intermediate in a modular fashion to complete the total synthesis of dictyodendrins A-E. A benzyne-mediated one-pot indoline formation/cross-coupling sequence is used for the construction of a highly substituted common indole intermediate. The peripheral substituents were introduced using a Friedel-Crafts reaction on the indole intermediate in a modular fashion to complete the total synthesis. Copyright

Total synthesis of dictyodendrin A and B

Okano, Kentaro,Fujiwara, Hideto,Noji, Toshiharu,Fukuyama, Tohru,Tokuyama, Hidetoshi

supporting information; experimental part, p. 5925 - 5929 (2010/10/03)

(Figure Presented) In-do-line of fire: A highly efficient total synthesis of the title compounds features a novel benzyne-mediated one-pot indoline formation/cross-coupling sequence for the construction of a highly substituted key indoline intermediate. The peripheral substituents were then introduced onto the intermediate in a modular fashion to complete the total syntheses of dictyodendrin A and B.

N4-Phenyl modifications of N2-(2-hydroxyl)ethyl-6-(pyrrolidin-1-yl)-1,3,5-triazine-2,4-d iamines enhance glucocerebrosidase inhibition by small molecules with potential as chemical chaperones for Gaucher disease

Huang, Wenwei,Zheng, Wei,Urban, Daniel J.,Inglese, James,Sidransky, Ellen,Austin, Christopher P.,Thomas, Craig J.

, p. 5783 - 5789 (2008/02/13)

A series of 1,3,5-triazine-2,4,6-triamines were prepared and analyzed as inhibitors of glucocerebrosidase. Synthesis, structure activity relationships and the selectivity of chosen analogues against related sugar hydrolases enzymes are described.

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