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127554-90-9

trans-Carboxy Glimepiride is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 4-[[4-[2-[(4-ethyl-3-methyl-5-oxo-2H-pyrrole-1-carbonyl)amino]ethyl]phenyl]sulfonylcarbamoylamino]cyclohexane-1-carboxylic acid

    Cas No: 127554-90-9

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  • 127554-90-9 Structure

  • Basic information

    1. Product Name: trans-Carboxy Glimepiride
    2. Synonyms: trans-Carboxy Glimepiride;trans-4-[[[[[4-[2-[[(3-Ethyl-2,5-dihydro-4-Methyl-2-oxo-1H-pyrrol-1-yl)carbonyl]aMino]ethyl]phenyl]sulfonyl]aMino]carbonyl]aMino]cyclohexanecarboxylic Acid
    3. CAS NO:127554-90-9
    4. Molecular Formula: C25H34N4O7S
    5. Molecular Weight: 534.62506
    6. EINECS: N/A
    7. Product Categories: Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Sulfur & Selenium Compounds;Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
    8. Mol File: 127554-90-9.mol

  • Chemical Properties

    1. Melting Point: 111-115°C
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.396g/cm3
    6. Refractive Index: 1.621
    7. Storage Temp.: -20°C Freezer
    8. Solubility: DMSO (Slightly), Ethyl Acetate (Heated, Sonicated), Methanol (Sparingly)
    9. Stability: Hygroscopic
    10. CAS DataBase Reference: trans-Carboxy Glimepiride(CAS DataBase Reference)
    11. NIST Chemistry Reference: trans-Carboxy Glimepiride(127554-90-9)
    12. EPA Substance Registry System: trans-Carboxy Glimepiride(127554-90-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 127554-90-9(Hazardous Substances Data)

127554-90-9 Usage

Chemical Properties

White to Off-White Solid

Uses

An active metabolite of Glimepiride (G410150).

Check Digit Verification of cas no

The CAS Registry Mumber 127554-90-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,5,5 and 4 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 127554-90:
(8*1)+(7*2)+(6*7)+(5*5)+(4*5)+(3*4)+(2*9)+(1*0)=139
139 % 10 = 9
So 127554-90-9 is a valid CAS Registry Number.
InChI:InChI=1/C24H32N4O7S/c1-3-20-15(2)14-28(21(20)29)24(33)25-13-12-16-4-10-19(11-5-16)36(34,35)27-23(32)26-18-8-6-17(7-9-18)22(30)31/h4-5,10-11,17-18H,3,6-9,12-14H2,1-2H3,(H,25,33)(H,30,31)(H2,26,27,32)/t17-,18-

127554-90-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-[[4-[2-[(4-ethyl-3-methyl-5-oxo-2H-pyrrole-1-carbonyl)amino]ethyl]phenyl]sulfonylcarbamoylamino]cyclohexane-1-carboxylic acid

1.2 Other means of identification

Product number -
Other names trans-Carboxy Glimepiride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:127554-90-9 SDS

127554-90-9Downstream Products

127554-90-9Relevant articles and documents

EX VIVO METHODS FOR PREDICTING AND CONFIRMING IN VIVO METABOLISM OF PHARMACEUTICALLY ACTIVE COMPOUNDS

-

Page/Page column 34; 35; 36, (2015/06/25)

Methods and compositions for the catalytic oxidation of pharmaceutically active compounds, and more particularly to ex vivo methods for predicting in vivo metabolism of pharmaceutically active compounds, including predicting in vivo interaction between two or more pharmaceutically active compounds.

Sex difference in pharmacokinetics of the novel sulfonylurea antidiabetic glimepiride in rats

Yamazaki,Tabata

, p. 1317 - 1321 (2007/10/02)

Glimepiride (Hoe 490, CAS 93479-97-1), a novel sulfonylurea antidiabetic agent, was studied for the cause of sex-related difference in the elimination clearance of the unchanged drug in rats. After intravenous and oral administration, the serum level of t

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