127733-47-5

Basic information

• Product Name: (R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE
• Synonyms: (R)-1-(3,5-BIS(TRIFLUOROMETHYL)PHENYL)ETHANAMINE;(R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE;(R)-1-[BIS-3,5-(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE;R-MBT-PEM;Benzenemethanamine, α-methyl-3,5-bis(trifluoromethyl)-, (αR)-;(R)-1-(3,5-bis(trifluoromethyl)phenyl)ethan-1-amine;Benzenemethanamine, a-methyl-3,5-bis(trifluoromethyl)-,(aR)-
• CAS NO: 127733-47-5
• Molecular Formula: C₁₀H₉F₆N
• Molecular Weight: 257.18
• Product Categories: API intermediates
• Mol File: 127733-47-5.mol

Chemical Properties

• Boiling Point: 168.856 °C at 760 mmHg
• Flash Point: 66.334 °C
• Appearance: /
• Density: 1.328 g/cm³
• Vapor Pressure: 1.59mmHg at 25°C
• Refractive Index: 1.422
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE(127733-47-5)
• EPA Substance Registry System: (R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE(127733-47-5)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• Hazardous Substances Data: 127733-47-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE is used as a key intermediate in the synthesis of various pharmaceutical compounds, particularly for the development of highly potent thiourea inhibitors of cytomegalovirus. These inhibitors play a crucial role in the treatment of cytomegalovirus infections, which can be severe and life-threatening in immunocompromised individuals.
In the pharmaceutical industry, (R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE serves as a building block for the creation of new drugs targeting cytomegalovirus, a significant pathogen that can cause various health issues, especially in individuals with weakened immune systems. The compound's unique structure allows for the design of effective inhibitors that can help combat the virus and improve patient outcomes.

InChI:InChI=1/C10H9F6N/c1-5(17)6-2-7(9(11,12)13)4-8(3-6)10(14,15)16/h2-5H,17H2,1H3/t5-/m1/s1

Upstream product

• 187085-97-8 (RS)-α-methyl-3,5-bis(trifluoromethyl)benzenemethanamine 
• 384824-39-9 C₈H₈O₃*C₁₀H₉F₆N 
• 384824-37-7 C₄H₆O₆*C₁₀H₉F₆N 
• 384824-36-6 C₇H₈O₃S*C₁₀H₉F₆N 
• 384824-41-3 [(S)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-amine 
• 511256-29-4 [(R)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethyl]-((S)-1-phenyl-ethyl)-amine 
• 672906-98-8 [1-(3,5-Bis-trifluoromethyl-phenyl)-eth-(E)-ylidene]-((S)-1-phenyl-ethyl)-amine 
• 30071-93-3 3,5-bis(trifluoromethyl)phenyl methyl ketone 
• 742097-67-2 N-(1-(3,5-bis(trifluoromethyl)phenyl)ethyl)formamide 
• 127733-38-4 3,5-bis(trifluoromethyl)acetophenone O-methyloxime 

Downstream Products

• 384824-39-9 C₈H₈O₃*C₁₀H₉F₆N 
• 384824-36-6 C₇H₈O₃S*C₁₀H₉F₆N 

Relevant articles and documents

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