127743-98-0Relevant articles and documents
Benzoyl Fluorides as Fluorination Reagents: Reconstruction of Acyl Fluorides via Reversible Acyl C-F Bond Cleavage/Formation in Palladium Catalysis
Ogiwara, Yohei,Hosaka, Shintaro,Sakai, Norio
, p. 856 - 861 (2020)
This report describes the formation of value-added acyl fluorides by means of palladium-catalyzed acyl-exchange reactions between acyl fluorides and acid anhydrides. This method allows using a simple and commercially available acyl fluoride, benzoyl fluoride, as the fluoride source for the easy and efficient preparation of a variety of more complex acyl fluorides. The results of this study suggest that this reaction proceeds via a reversible acyl C-F bond cleavage/formation at the palladium center.
Acyl fluorides as direct precursors to fluoride ketyl radicals: Reductive deuteration using SmI2and D2O
Li, Hengzhao,Peng, Mengqi,Lai, Zemin,Ning, Lei,Chen, Xingyue,Zhang, Xiaoxu,Wang, Pengjie,Szostak, Roman,Szostak, Michal,An, Jie
supporting information, p. 5195 - 5198 (2021/05/31)
A highly chemoselective reductive deuteration of acyl fluorides to provide α,α-dideuterio alcohols with exquisite levels of deuterium incorporation was developed using SmI2 and D2O as the deuterium source. This method introduces acyl fluorides as attracti
