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Ethanone,1-(4-amino-6-methyl-3-pyridinyl)-, also known as 4-Amino-6-methyl-3-pyridinyl methyl ketone, is a pyridinyl compound with a molecular formula of C8H10N2O. It features a ketone functional group and is widely used as a versatile building block in organic chemistry. This chemical is essential in the synthesis of pharmaceuticals, agricultural chemicals, and various organic compounds, making it a crucial intermediate in the production of drugs and other biologically active molecules.

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  • 127915-47-3 Structure
  • Basic information

    1. Product Name: Ethanone,1-(4-amino-6-methyl-3-pyridinyl)-
    2. Synonyms: Ethanone,1-(4-amino-6-methyl-3-pyridinyl)-;Ethanone, 1-(4-amino-6-methyl-3-pyridinyl)- (9CI);1-(4-aMino-6-Methylpyridin-3-yl)ethanone
    3. CAS NO:127915-47-3
    4. Molecular Formula: C8H10N2O
    5. Molecular Weight: 150.1778
    6. EINECS: N/A
    7. Product Categories: ACETYLGROUP;AMINEPRIMARY;PYRIDINE
    8. Mol File: 127915-47-3.mol
  • Chemical Properties

    1. Melting Point: 133 °C(Solv: carbon tetrachloride (56-23-5))
    2. Boiling Point: 326.9±37.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.131±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. PKA: 7.51±0.42(Predicted)
    10. CAS DataBase Reference: Ethanone,1-(4-amino-6-methyl-3-pyridinyl)-(CAS DataBase Reference)
    11. NIST Chemistry Reference: Ethanone,1-(4-amino-6-methyl-3-pyridinyl)-(127915-47-3)
    12. EPA Substance Registry System: Ethanone,1-(4-amino-6-methyl-3-pyridinyl)-(127915-47-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 127915-47-3(Hazardous Substances Data)

127915-47-3 Usage

Uses

Used in Pharmaceutical Industry:
Ethanone,1-(4-amino-6-methyl-3-pyridinyl)is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to form complex molecular structures. Its presence in the molecular composition of drugs contributes to their therapeutic effects and medicinal properties.
Used in Agricultural Chemical Industry:
In the agricultural sector, Ethanone,1-(4-amino-6-methyl-3-pyridinyl)is utilized as a precursor in the production of agricultural chemicals. Its unique chemical structure allows for the development of effective compounds that can be used in crop protection and pest control.
Used in Organic Chemistry Research:
As a versatile building block, Ethanone,1-(4-amino-6-methyl-3-pyridinyl)is employed in organic chemistry research for the synthesis of new organic compounds. Its reactivity and functional groups enable the creation of a wide range of molecules with potential applications in various fields.
Used in the Production of Biologically Active Molecules:
Ethanone,1-(4-amino-6-methyl-3-pyridinyl)is used as a starting material in the synthesis of biologically active molecules. Its unique structure allows for the development of compounds with specific biological activities, making it a valuable asset in the discovery and production of new therapeutic agents and other bioactive substances.

Check Digit Verification of cas no

The CAS Registry Mumber 127915-47-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,9,1 and 5 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 127915-47:
(8*1)+(7*2)+(6*7)+(5*9)+(4*1)+(3*5)+(2*4)+(1*7)=143
143 % 10 = 3
So 127915-47-3 is a valid CAS Registry Number.

127915-47-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(4-amino-6-methylpyridin-3-yl)ethanone

1.2 Other means of identification

Product number -
Other names 5-Acetyl-4-amino-2-methylpyridin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:127915-47-3 SDS

127915-47-3Relevant articles and documents

Improved Synthesis of N1-Pyridylthiamine Pyrophosphate, a Coenzymatically Active Analog of Thiamine Pyrophosphate

Neef, Holger,Golbik, Ralph,Fahlbusch, Baerbel,Schellenberger, Alfred

, p. 913 - 916 (2007/10/02)

Our previously published synthesis of the N1-pyridyl analog 1b of thiamine pyrophosphate is improved resulting in a remarkably higher yield.Key reaction of this new synthetic pathway is the oxidative degradation of 5-acetylpyridine 8 to the 5-carboxylic acid 11 via the pyridinium compound 10.Improved preparations of other intermediates are also described.The N1-pyridylthiamine pyrophosphate analog 1b has been separated and purified by ion exchange chromatography on Sephadex A-25.

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