Transition-state analogue inhibitors of chorismate mutase
The synthesis of seven bi- and tricyclic chorismate analogues 9-15 and their biological evaluation as mutase inhibitors is described. A tandem Cope rearrangement/Diels-Alder cycloaddition strategy was employed to prepare tricyclo[3.3.1.02,7]non
Clarke, Trafford,Stewart, Jon D.,Ganem, Bruce
p. 731 - 748
(2007/10/02)
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