128073-09-6

Basic information

• Product Name: 3-Chloro-5-Methoxy-2-pyridinecarboxylic acid
• Synonyms: 3-Chloro-5-Methoxy-2-pyridinecarboxylic acid;3-Chloro-5-Methoxypicolinic acid;3-Chloro-5-methoxy-pyridine-2-carboxylic acid
• CAS NO: 128073-09-6
• Molecular Formula: C7H6ClNO3
• Molecular Weight: 187.58044
• Mol File: 128073-09-6.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 3-Chloro-5-Methoxy-2-pyridinecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloro-5-Methoxy-2-pyridinecarboxylic acid(128073-09-6)
• EPA Substance Registry System: 3-Chloro-5-Methoxy-2-pyridinecarboxylic acid(128073-09-6)

Safety Data

• Hazardous Substances Data: 128073-09-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
3-Chloro-5-Methoxy-2-pyridinecarboxylic acid is utilized as a key intermediate in the synthesis of pharmaceuticals. Its presence in the molecular structure allows for the development of new drug treatments, particularly due to its antimicrobial and antibacterial properties, which make it a promising candidate for addressing various health concerns.
Used in Agrochemical Production:
In the agrochemical industry, 3-Chloro-5-Methoxy-2-pyridinecarboxylic acid is employed as a vital component in the creation of pesticides and other agricultural chemicals. Its ability to combat microbial threats contributes to enhancing crop protection and yield.
Used as an Antimicrobial Agent:
3-Chloro-5-Methoxy-2-pyridinecarboxylic acid is used as an antimicrobial agent for its inherent ability to inhibit the growth of microorganisms. This makes it suitable for applications where microbial control is necessary, such as in medical, food preservation, and water treatment processes.
Used in Organic Synthesis:
As an important intermediate in organic synthesis, 3-Chloro-5-Methoxy-2-pyridinecarboxylic acid is used in the manufacturing of a variety of chemical products. Its versatility in chemical reactions allows it to be a component in the synthesis of complex organic molecules for different industries.

Upstream product

• 128073-14-3 methyl 3-chloro-5-methoxypicolinate 
• 1256811-09-2 methyl 3-chloro-5-hydroxypicolinate 

Downstream Products

• 1624603-55-9 N-(3-((4S,6S)-2-amino-4-(fluoromethyl)-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl)-4-fluorophenyl)-3-chloro-5-methoxypicolinamide 
• 1624604-69-8 N-(3-((4S,6S)-2-amino-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl)-4,5-difluorophenyl)-3-chloro-5-methoxypicolinamide 

Relevant articles and documents

PERFLUORINATED CYCLOPROPYL FUSED 1,3-OXAZIN-2-AMINE COMPOUNDS AS BETA-SECRETASE INHIBITORS AND METHODS OF USE

PERFLUORINATED CYCLOPROPYL FUSED 1,3-OXAZIN-2-AMINE COMPOUNDS AS BETA-SECRETASE INHIBITORS AND METHODS OF USE ABSTRACT OF THE DISCLOSURE The present invention provides a new class of compounds useful for the modulation of beta-secretase enzyme (BACE) activity. The compounds have a general Formula I: {INSERT STRUCTURE HERE} I wherein variables A4, A5, A6, A8, each of Ra, Rb, R1, R2, R3 and R7 of Formula I, independently, are defined herein. The invention also provides pharmaceutical compositions comprising the compounds, and uses of the compounds and compositions for treatment of disorders and/or conditions related to A-beta plaque formation and deposition, resulting from the biological activity of BACE. Such BACE mediated disorders include, for example, Alzheimer's Disease, cognitive deficits, cognitive impairments, schizophrenia and other central nervous system conditions. The invention further provides compounds of Formulas II and III, and sub-formula embodiments thereof, intermediates and methods for preparing compounds of the invention.

FUSED MULTI-CYCLIC SULFONE COMPOUNDS AS INHIBITORS OF BETA-SECRETASE AND METHODS OF USE THEREOF

The present invention provides a new class of compounds useful for the modulation of beta-secretase enzyme (BACE) activity. The compounds have a general Formula I: wherein variables A5, A6, A8, R1, R2, R3, R7, X, Y, n and o of Formula I, independently, are defined herein. The invention also provides pharmaceutical compositions comprising the compounds, and corresponding uses of the compounds and compositions for treatment of disorders and/or conditions related to A-beta plaque formation and deposition, resulting from the biological activity of BACE. Such BACE mediated disorders include, for example, Alzheimer's Disease, cognitive deficits, cognitive impairments, schizophrenia and other central nervous system conditions. The invention further provides compounds of Formula II and sub-formula embodiments thereof, compounds of Formula III, intermediates and processes and methods useful for the preparation of compounds of Formulas I-III, and sub-Formulas thereof.

PERFLUORINATED 5,6-DIHYDRO-4H-1,3-OXAZIN-2-AMINE COMPOUNDS AS BETA-SECRETASE INHIBITORS AND METHODS OF USE

The present invention provides a new class of compounds useful for the modulation of beta-secretase enzyme (BACE) activity. The compounds have a general Formula I: wherein variables A4, A5, A6, A8, each of R1 and R2, R3 and R7 of Formula I, independently, are defined herein. The invention also provides pharmaceutical compositions comprising the compounds, and corresponding uses of the compounds and compositions for treatment of disorders and/or conditions related to A-beta plaque formation and deposition, resulting from the biological activity of BACE. Such BACE mediated disorders include, for example, Alzheimer's Disease, cognitive deficits, cognitive impairments, schizophrenia and other central nervous system conditions. The invention further provides compounds of Formulas II and III, and sub-formula embodiments thereof, intermediates and processes and methods useful for the preparation of compounds of Formulas I-III.