Phosphate mediated biomimetic synthesis of tetrahydroisoquinoline alkaloids
A one-pot synthesis of tetrahydroisoquinoline alkaloids in a phosphate buffer has been achieved, and a reaction mechanism proposed. The utilisation of mild reaction conditions readily afforded a range of isoquinolines, including norcoclaurine.
Pesnot, Thomas,Gershater, Markus C.,Ward, John M.,Hailes, Helen C.
supporting information; experimental part
p. 3242 - 3244
(2011/05/05)
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