- Novel, versatile three-step synthesis of 1,2,3,4,10,10a-hexahydro- pyrazino[1,2- a ]indoles by intramolecular carbene-mediated C-H insertion
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A new convenient three-step synthesis of the privileged CNS scaffold 1,2,3,4,10,10a-hexahydropyrazino[1,2-a]indoles has been developed. The method makes use of an intramolecular carbene-mediated C-H insertion in phenylpiperazine-derived tosyl-hydrazones m
- Krogsgaard-Larsen, Niels,Begtrup, Mikael,Herth, Matthias M.,Kehler, Jan
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experimental part
p. 4287 - 4299
(2011/02/22)
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