128758-05-4

Basic information

• Product Name: 1-PHENYLOCTAHYDROPYRROLO[3,4-B]PYRROLE
• Synonyms: 1-PHENYLOCTAHYDROPYRROLO[3,4-B]PYRROLE
• CAS NO: 128758-05-4
• Molecular Formula: C12H16N2
• Molecular Weight: 188.26884
• Mol File: 128758-05-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-PHENYLOCTAHYDROPYRROLO[3,4-B]PYRROLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PHENYLOCTAHYDROPYRROLO[3,4-B]PYRROLE(128758-05-4)
• EPA Substance Registry System: 1-PHENYLOCTAHYDROPYRROLO[3,4-B]PYRROLE(128758-05-4)

Safety Data

• Hazardous Substances Data: 128758-05-4(Hazardous Substances Data)

Upstream product

• 132414-84-7 ethyl 2-phenyl-2,7-diazabicyclo[3.3.0]octane-7-carboxylate 

Relevant articles and documents

DOPAMINE D3 RECEPTOR ANTAGONISTS HAVING A BICYCLO MOIETY

The disclosure provides compounds having formula (I), wherein the substituents are as defined herein. The compounds are useful for modulating the dopamine D3 receptor and for treating conditions associated therewith, such as addictions, drug dependency, and psychiatric conditions.

7-(2,7-diazabicyclo[3.3.0]octyl)-3-quinoline- and -naphthyridone-carboxylic acid derivatives

The invention relates to new 7-(2,7-Diazabicyclo[3.3.0]octyl)-3-quinolone- and -naphthyridonecarboxylic acid derivatives, processes for their preparation, and antibacterial agents and feed additives containing them.

7-(1-PYRROLIDINYL)-3-QUINOLONE-AND-NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS AND FEED ADDITIVES

7-(1-Pyrrolidinyl)-3-quinolone- and -naphthyridonecarboxylic acid derivatives as antibacterial agents and feed additives, of the formula in which X1 is halogen, X2 is hydrogen, halogen, amino or other radical, R1 is alkyl, cycloalkyl, optionally substituted phenyl or other radical, R2 is hydrogen, alkyl or a dioxolylmethyl radical, R 3 i s A is N, CH, C-halogen, or the like, or forms a bridge with R1, and addition products thereof

Preparation of 2,7-diazabicyclo[3.3.0]octanes

2,7-Diazabicyclo[3.3.0]octanes, suitable for 7-position substituents or antibacterially active quinolone carboxylic acids, of the formula STR1 in which R1, R3, R4, R5, R7 and R8 may be identical or different and in each case denote H, C1 -C5 -alkyl (optionally substituted by halogen, hydroxyl or C1 -C3 -alkoxy), C1 -C3 -alkoxycarbonyl or C6 -C12 -aryl, R4 additionally denotes halogen, R2 and R6 may be identical or different, denote H, C1 -C6 -alkyl, benzyl, C6 -C12 -aryl, C1 -C3 -alkanoyl, benzoyl or C1 -C5 -alkoxycarbonyl, or R2 and R3 together denote a bridge of the structure (CH2)n, n=2-4, CH2 --CHOH--CH2, CH2 --S--CH2 or C(CH3)2 --S--CH2, excluding 2,7-diazabicyclo[3.3.0]octane. Also their preparation by the reaction STR2 Intermediates II are also new.