128960-23-6

Basic information

• Product Name: 2-(ethylsulfanyl)pentanamide
• CAS NO: 128960-23-6
• Molecular Formula: C₇H₁₅NOS
• Molecular Weight: 161.2651
• Mol File: 128960-23-6.mol

Chemical Properties

• Boiling Point: 279.6°C at 760 mmHg
• Flash Point: 122.9°C
• Density: 1.012g/cm³
• Vapor Pressure: 0.00397mmHg at 25°C
• Refractive Index: 1.489
• CAS DataBase Reference: 2-(ethylsulfanyl)pentanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(ethylsulfanyl)pentanamide(128960-23-6)
• EPA Substance Registry System: 2-(ethylsulfanyl)pentanamide(128960-23-6)

Safety Data

• Hazardous Substances Data: 128960-23-6(Hazardous Substances Data)

Upstream product

• 59863-66-0 bromo-N-propylacetamide 
• 75-08-1 ethanethiol 
• 60340-33-2 2-propyl-3-thiapentanenitrile 
• 42768-45-6 2-bromopentanoyl chloride 

Relevant articles and documents

POTENTIAL ANTICONVULSANTS: SOME DERIVATIVES AND ANALOGUES OF 2-PROPYLPENTANOIC ACID

Reaction of 2-(ethoxycarbonylamino)ethanol with 2-propylpentanoyl chloride gave the ester III.N-(4-Piperidinyl)-2-propylpentanamide (V) was prepared via the 1-benzyl-4-piperidinyl derivative IV and was acylated with ethanesulfonyl chloride and 2-propylpentanoyl chloride to give the amides VI and VII.Malonic ester syntheses afforded diethyl 2-ethyl- and 2-propyl-2-(2(methylthio)ethyl)malonate VIII and XIII which were hydrolyzed and decarboxylated to the acids X and XV which, in turn, were transformed to the amides XII and XVII. 3-Thiapentanenitrile was alkylated with propyl bromide to the nitrile XIX which was hydrolyzed to the acid XX and the amide XXI.The acids X, XV, and XX, and the amides XII, XVII, and XXI are analogues of the anticonvulsant agents valproic acid (I) and valpromide (II).Compounds XX (VFB-14 721) and XXI (VFB-14 722) potentiate, in doses in which they "per se" are ineffective as anticonvulsants in mice, significantly the anticonvulsant effect of diazepam.