128962-66-3Relevant articles and documents
Synthesis of a core disaccharide from the Streptococcus pneumoniae type 23F capsular polysaccharide antigen
Dasgupta, Somnath,Nitz, Mark
experimental part, p. 2282 - 2286 (2010/12/19)
The synthesis of methyl α-l-rhamnopyranosyl-(1→2)-β-d- galactopyranoside and methyl α-l-rhamnopyranosyl-(1→2)-3-(glycer-2- yl-phosphate)-β-d-galactopyranoside disaccharides from the Streptococcus pneumoniae type 23F capsular polysaccharide is reported. A simple protecting group strategy was followed using commercially available monosaccharides and phosphorylating reagents. H-Phosphonate and phosphoramidite coupling chemistries were explored for introducing the phosphodiester. Hydrazine hydrate was found to be a mild and efficient deacetylating agent, which was required to avoid phosphate migration during the deprotection of the phosphodiester functionalized disaccharide.
Synthesis of di- and tri-saccharides related to the polysaccharide from Streptococcus pneumoniae type 23 and a study of their inhibition in the precipitin reaction.
Ray,Maddali,Roy,Roy
, p. 93 - 100 (2007/10/02)
Syntheses of methyl 2-O-beta-L-rhamnopyranosyl-beta-D-galactopyranoside (9), methyl 2-O-alpha-L-rhamnopyranosyl-beta-D-galactopyranoside (13), and methyl 4-O-beta-D-glucopyranosyl-2-O-alpha-L-rhamnopyranosyl-beta-D- galactopyranoside (16) in good yields a
