129322-81-2

Basic information

• Product Name: 1-(2-Chloro-4-(trifluoroMethyl)phenyl)ethanone
• Synonyms: 1-(2-Chloro-4-(trifluoroMethyl)phenyl)ethanone;1-(2-Chloro-4-(trifluoromethyl);2'-chloro-4'-(trifluoromethyl)acetophenone
• CAS NO: 129322-81-2
• Molecular Formula: C₉H₆ClF₃O
• Molecular Weight: 222.5915496
• Mol File: 129322-81-2.mol

Chemical Properties

• Boiling Point: 80-81 °C(Press: 7.5 Torr)
• Appearance: /
• Density: 1.337±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-(2-Chloro-4-(trifluoroMethyl)phenyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Chloro-4-(trifluoroMethyl)phenyl)ethanone(129322-81-2)
• EPA Substance Registry System: 1-(2-Chloro-4-(trifluoroMethyl)phenyl)ethanone(129322-81-2)

Safety Data

• Hazardous Substances Data: 129322-81-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-(2-Chloro-4-(trifluoroMethyl)phenyl)ethanone is used as a synthetic intermediate for the development of pharmaceuticals, contributing to the creation of new drugs and medicinal compounds. Its unique molecular structure allows for versatile chemical reactions, facilitating the synthesis of a wide range of pharmaceutical products.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(2-Chloro-4-(trifluoroMethyl)phenyl)ethanone is employed as a precursor in the synthesis of various agrochemicals, including pesticides and herbicides. Its reactivity and structural properties enable the production of effective and targeted agrochemicals to protect crops and enhance agricultural productivity.
Used in Organic Chemistry Research:
1-(2-Chloro-4-(trifluoroMethyl)phenyl)ethanone is utilized as a building block in organic chemistry research, allowing scientists to explore new chemical reactions and synthesize novel organic compounds. Its unique structure provides opportunities for innovative applications in the field of organic chemistry.
However, it is important to note that 1-(2-Chloro-4-(trifluoroMethyl)phenyl)ethanone has low water solubility and high volatility, which can pose potential hazards to human health and the environment. Therefore, strict safety guidelines and proper handling and storage measures must be followed when working with this chemical.

Downstream Products

• 1616406-11-1 2-(2-amino-5-(4-methylpiperazin-1-yl)-3H-imidazo[4,5-b]pyridin-3-yl)-1-(2-chloro-4-(trifluoromethyl)phenyl)ethan-1-one 
• 1616405-97-0 2-(2-amino-5-(4-methylpiperazin-1-yl)-3H-imidazo[4,5-b]pyridin-3-yl)-1-(2-chloro-4-(trifluoromethyl)phenyl)ethan-1-ol 
• 1616406-01-9 2-(2-amino-5-(2,2,2-trifluoroethoxy)-3H-imidazo[4,5-b]pyridin-3-yl)-1-(2-chloro-4-(trifluoromethyl)phenyl)ethanol 
• 1616406-02-0 2-(2-amino-5-((tetrahydrofuran-3-yl)oxy)-3H-imidazo[4,5-b]pyridin-3-yl)-1-(2-chloro-4-(trifluoromethyl)phenyl)ethanol 
• 1616406-04-2 2-(2-amino-5-((1,1,1-trifluoropropan-2-yl)oxy)-3H-imidazo[4,5-b]pyridin-3-yl)-1-(2-chloro-4-(trifluoromethyl)phenyl)ethanol 
• 1616406-05-3 2-(3-amino-5-cyclopropyl-4H-1,2,4-triazol-4-yl)-1-(2-chloro-4-(trifluoromethyl)phenyl)ethanol 
• 1616406-55-3 1-(2-chloro-4-(trifluoromethyl)phenyl)-2-(3-cyclopropyl-5-(2,5-dimethyl-1H-pyrrol-1-yl)-4H-1,2,4-triazol-4-yl)ethan-1-one 
• 1616406-56-4 1-(2-chloro-4-(trifluoromethyl)phenyl)-2-(3-cyclopropyl-5-(2,5-dimethyl-1H-pyrrol-1-yl)-4H-1,2,4-triazol-4-yl)ethan-1-ol 
• 1616405-85-6 2-(2-amino-4-(4-fluorophenyl)-1H-imidazol-1-yl)-1-(2-chloro-4-(trifluoromethyl)phenyl)ethanol 
• 1616406-41-7 2-(2-amino-5-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)-1-(2-chloro-4-(trifluoromethyl)phenyl)ethanol 
• 1616405-94-7 2-(2-amino-6-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)-1-(2-chloro-4-(trifluoromethyl)phenyl)ethanol 
• 1629243-73-7 1-(2-chloro-4-(trifluoromethyl)phenyl)-2-(2-(2,5-dimethyl-1H-pyrrol-1-yl)-4-(4-fluorophenyl)-1H-imidazol-1-yl)ethan-1-one 
• 1616406-28-0 1-(2-chloro-4-(trifluoromethyl)phenyl)-2-(2-(2,5-dimethyl-1H-pyrrol-1-yl)-4-(4-fluorophenyl)-1H-imidazol-1-yl)ethan-1-ol 
• 1616406-39-3 2-(2-amino-6-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)-1-(2-chloro-4-(trifluoromethyl)phenyl)ethanone 

Relevant articles and documents

Antimycotically active substituted 2-aminothiazoles

Antimicotically active 2-aminothiazoles have been found having the formula STR1 in which R1 represents hydrogen or alkyl and R2 represents optionally substituted cyclohexyl or phenyl which is substituted by halogen, alkyl, halogenoalkyl, halogenoalkoxy, dioxyhalogenoalkyl or halogenoalkylthio, and their physiologically tolerable acid addition salts, with the exception of the compounds 4-(4-chlorophenyl)-2-[2-(1,4,5,6-tetrahydropyrimidinyl)-amino]thiazole and 4-(2,4-dichlorophenyl)-2-[2-(1,4,5,6-tetrahydropyrimidinyl)-amino]-thiazole and 4-(4-chloro-2-methylphenyl)-2-[2-(1,4,5,6-tetrahydropyrimidinyl)-amino]-thiazole and with the exception of the physiologically tolerable acid addition salts of these compounds have been found.

Fluorine-containing acetophenones optionally halogenated on the CH3 -group and their precurser fluorine-containing benzonitriles

Fluorine-containing acetophenones, optionally halogenated on the CH3 group, of the formula STR1 in which X represents hydrogen, chlorine or bromine and the radicals R1 to R5 have the following meaning, a) R1 and R4 denote fluorine, R2 and R5 denote chlorine and R3 denotes CF3, or b) R1, R3 and R4 denote fluorine and R2 and R5 denote hydrogen, or c) R1, R4 and R5 denote hydrogen, R2 denotes chlorine and R3 denotes CF3, or d) R1, R4 and R5 denote hydrogen, R2 denotes chlorine and R3 denotes OCF3, or e) R1, R4 and R5 denote hydrogen and R2 and R3 denote CF3, or f) R1 denotes chlorine, R2 denotes CF3 and R3, R4 and R5 denote hydrogen, or g) R1 denotes chlorine, R2, R3 and R4 denote hydrogen and R5 denotes CF3, or h) R1 denotes chlorine, R2, R4 and R5 denote hydrogen and R3 denotes CF3 and a process for their preparation from the corresponding fluorinated benzonitriles or benzyl halides by reaction with an organomagnesium compound capable of introducing methyl groups and subsequent hydrolysis, if appropriate followed by a chlorination or bromination.