129414-04-6Relevant articles and documents
(2S,3S)-2-Amino-3-(2,2-diphenylethyl)pentanedioic acid selective group 2 metabotropic glutamate receptor antagonist
Escribano, Ana,Ezquerra, Jesus,Pedregal, Concepcion,Rubio, Almudena,Yruretagoyena, Belen,Baker, S. Richard,Wright, Rebecca A.,Johnson, Bryan G.,Schoepp, Darryle D.
, p. 765 - 770 (2007/10/03)
(2S,4S)-2-Amino-4-(4,4-diphenylbut-1-yl)-pentane-1,5-dioic acid 1m, is a novel metabotropic glutamate receptor (mGluR) antagonist with insignificant ionotropic affinity. It is a selective antagonist of negatively-coupled cAMP-linked mGluRs with no effect
SYNTHESES OF (2S,4S)- AND (2S,4R)-4-SUBSTITUTED GLUTAMIC ACID ANALOGUES FOR NEUROEXCITATORY ACTIVITY STUDIES
Hon, Yung-Son,Chang, Yen-Chung,Gong, Ming-Li
, p. 191 - 195 (2007/10/02)
The stereospecific syntheses of various lenght of 4(R)- and 4(S)-substituted 2(S)-glutamic acid were described.