Palladium-catalyzed hydrofunctionalization of vinyl phenol derivatives with heteroaromatics
A hydroheteroarylation reaction of vinyl phenols using an alkyl chloride as the sacrificial hydride source is reported. The method tolerates a wide range of heterocycles as the exogenous nucleophile including indoles and pyrroles. The resulting products are easily processed to biologically relevant scaffolds.
Pathak, Tejas P.,Sigman, Matthew S.
supporting information; experimental part
p. 2774 - 2777
(2011/06/25)
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