- Phosphane-catalyzed umpolung addition reaction of nucleophiles to ethyl 2-methyl-2,3-butadienoate
-
The phosphane-catalyzed umpolung addition of various nucleophiles to ethyl 2-methyl-2,3-butadienoate is described. Oxygen, nitrogen, and carbon nucleophiles smoothly reacted with ethyl 2-methyl-2,3-butadienoate to give the corresponding umpolung addition
- Guan, Xiao-Yang,Wei, Yin,Shi, Min
-
experimental part
p. 2673 - 2677
(2011/06/28)
-
- Phosphine-catalyzed β′-umpolung addition of nucleophiles to activated α-alkyl allenes
-
Highly functionalized alkenes can be prepared through phosphine-catalyzed β′-umpolung additions of nucleophiles (carbon-, oxygen-, nitrogen-, and sulfur-centered) to activated α-disubstituted allenes, providing many potentially useful synthetic intermediates in good to excellent yields, often with high levels of stereoselectivity for the product olefin geometry. Various substitution patterns around the allene are compatible with the process, showcasing the synthetic utility of allenes under the conditions of nucleophilic phosphine catalysis.
- Martin, Tioga J.,Vakhshori, Venus G.,Tran, Yang S.,Kwon, Ohyun
-
supporting information; experimental part
p. 2586 - 2589
(2011/06/25)
-