129661-58-1Relevant articles and documents
Functional derivatives of 1-methyl 2-formyl 5-nitroimidazole. Evaluation of their antiparasitic activities
Vanelle,Maldonado,Jentzer,Crozet,Savornin,Delmas,Gasquet,Timon-David
, p. 321 - 325 (2007/10/02)
New imidazole compounds with pharmacological activity were obtained after subjecting 1-methyl-2-formyl-5-nitroimidazole to classical organic reactions: aldimine production, Knoevenagel reaction, and 4-ylidenebutenolide production. Some of these compounds exhibit significant antiparasitic activities against amoebae, trichomonas and leishmania.