Functional derivatives of 1-methyl 2-formyl 5-nitroimidazole. Evaluation of their antiparasitic activities
New imidazole compounds with pharmacological activity were obtained after subjecting 1-methyl-2-formyl-5-nitroimidazole to classical organic reactions: aldimine production, Knoevenagel reaction, and 4-ylidenebutenolide production. Some of these compounds exhibit significant antiparasitic activities against amoebae, trichomonas and leishmania.