Enantiodivergent transannular rearrangement of 3-isopropyl-1,4- benzodiazepine-2,5-dione by memory of chirality
An unprecedented reactivity has been introduced to 3-isopropyl-1,4- benzodiazepine-2,5-dione thanks to N-Boc activation. Under basic conditions, a transannular rearrangement occurred by ring contraction to furnish a 3-aminoquinoline-2,4-dione with good to
Farran, Daniel,Archirel, Pierre,Toupet, Loic,Martinez, Jean,Dewynter, Georges