129894-63-9 Usage
Uses
Used in Pharmaceutical Industry:
Benzenemethanol,-(aminomethyl)-4-nitro-,(S)is used as a reagent in organic synthesis, particularly for the production of various drugs. Its unique structure allows it to be a key component in the creation of medicinal compounds.
Used in Antibacterial Applications:
Benzenemethanol,-(aminomethyl)-4-nitro-,(S)is known to exhibit antibacterial properties, making it a potentially useful ingredient in the development of new medications aimed at combating bacterial infections.
Used in Antifungal Applications:
Benzenemethanol,-(aminomethyl)-4-nitro-,(S)also shows antifungal characteristics, which positions it as a candidate for inclusion in medications designed to treat fungal infections.
Used in Organic Synthesis:
As a building block, Benzenemethanol,-(aminomethyl)-4-nitro-,(S)is utilized in the synthesis of a variety of organic compounds, contributing to the development of new chemical entities for different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 129894-63-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,8,9 and 4 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 129894-63:
(8*1)+(7*2)+(6*9)+(5*8)+(4*9)+(3*4)+(2*6)+(1*3)=179
179 % 10 = 9
So 129894-63-9 is a valid CAS Registry Number.
129894-63-9Relevant articles and documents
Enantioselective Aminohydroxylation of Styrenyl Olefins Catalyzed by an Engineered Hemoprotein
Cho, Inha,Prier, Christopher K.,Jia, Zhi-Jun,Zhang, Ruijie K.,G?rbe, Tamás,Arnold, Frances H.
supporting information, p. 3138 - 3142 (2019/02/01)
Chiral 1,2-amino alcohols are widely represented in biologically active compounds from neurotransmitters to antivirals. While many synthetic methods have been developed for accessing amino alcohols, the direct aminohydroxylation of alkenes to unprotected, enantioenriched amino alcohols remains a challenge. Using directed evolution, we have engineered a hemoprotein biocatalyst based on a thermostable cytochrome c that directly transforms alkenes to amino alcohols with high enantioselectivity (up to 2500 TTN and 90 % ee) under anaerobic conditions with O-pivaloylhydroxylamine as an aminating reagent. The reaction is proposed to proceed via a reactive iron-nitrogen species generated in the enzyme active site, enabling tuning of the catalyst's activity and selectivity by protein engineering.
