Synthesis and antitumor activity of duocarmycin derivatives
A series of duocarmycin B2 derivatives, modified at the phenolic hydroxyl group to ester, carbonate and carbamate, was synthesized. Antitumor activity of these analogs was preliminarily evaluated by assays of growth inhibition of HeLa S3 cells (in vitro)
Nagamura,Kanda,Kobayashi,Gomi,Saito
p. 1530 - 1535
(2007/10/03)
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