129960-45-8

Basic information

• Product Name: OTAVA-BB 1287452
• Synonyms: 2-(3,5-DICHLOROPHENYL)PROPAN-2-AMINE;OTAVA-BB 1287452
• CAS NO: 129960-45-8
• Molecular Formula: C₉H₁₁Cl₂N
• Molecular Weight: 204.099
• Mol File: 129960-45-8.mol

Chemical Properties

• Boiling Point: 249.7±25.0 °C(Predicted)
• Appearance: /
• Density: 1.220±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 8.74±0.10(Predicted)
• CAS DataBase Reference: OTAVA-BB 1287452(CAS DataBase Reference)
• NIST Chemistry Reference: OTAVA-BB 1287452(129960-45-8)
• EPA Substance Registry System: OTAVA-BB 1287452(129960-45-8)

Safety Data

• Hazardous Substances Data: 129960-45-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Development:
OTAVA-BB 1287452 is used as a potential drug target for the treatment of neoplasms and nervous system diseases, due to its unique chemical structure and classification as a sulfonamide.
Used in Chemical and Biological Research:
OTAVA-BB 1287452 is used as a reference compound in drug discovery, allowing researchers to study its effects on specific biological pathways and explore its potential as a therapeutic agent.
Used in Medicinal Chemistry:
OTAVA-BB 1287452 is utilized in the development of new pharmaceuticals, given its potential pharmacological uses and the possibility of it serving as a valuable tool in the advancement of medicinal chemistry.

Upstream product

• 68575-35-9 2-(3,5-dichlorophenyl)propan-2-ol 
• 65432-04-4 1,3-dichloro-5-isopropylbenzene 

Downstream Products

• 848031-10-7 1-[1-(3,5-dichloro-phenyl)-1-methyl-ethyl]-3-(2-fluoro-phenyl)-4-methyl-pyrrole-2,5-dione 
• 848031-11-8 1-[1-(3,5-dichloro-phenyl)-1-methyl-ethyl]-3-(3-fluoro-phenyl)-4-methyl-pyrrole-2,5-dione 
• 848031-12-9 3-(4-chloro-2-fluoro-phenyl)-1-[1-(3,5-dichloro-phenyl)-1-methyl-ethyl]-4-methyl-pyrrole-2,5-dione 
• 153197-75-2 N-methylene-1-methyl-1-(3,5-dichloro-phenyl)ethylamine 
• 959131-43-2 2-[3-(4-chlorophenyl)-4-cyclopropyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-N-[1-(3,5-dichlorophenyl)-1-methylethyl]acetamide 

Relevant articles and documents

3. 5 - dichloro - α, α - dimethyl benzylamine synthesis process (by machine translation)

The invention belongs to the field of pharmaceutical chemistry, relates to 3, 5 - dichloro - α, α - dimethyl benzylamine synthesis process, specific steps are as follows: (1) to 3, 5 - dichloro cumene in the halo illumination conditions, produce the 3, 5 - dichloro - α - halogenated cumene; (2) 3, 5 - dichloro - α - halogenated cumene in the reaction solvent in the reaction with the ammonia 3, 5 - dichloro - α, α - dimethyl benzylamine. The invention through the 3, 5 - dichloro cumene, in illumination next bromination, then mellow amine solution, to obtain 3, 5 - dichloro - α, α - dimethyl benzylamine. Its low raw material cost, easy to use, convenient to industrial production. (by machine translation)

NITROGEN-CONTAINING SATURATED HETEROCYCLIC COMPOUND

The present invention provides a compound represented by the following formula (I) or its pharmaceutically acceptable salt: [wherein, R1 represents optionally substituted C1-4 alkyl, n shows integer of 1 to 4, R2 represents optionally substituted C1-4 alkyl or hydrogen atom, R3 represents optionally substituted C1-4 alkyl, R4a, R4b, R4c, and R4d, similarly or differently, represent optionally substituted C6-14 aryl, optionally substituted C1-4 alkyl, or hydrogen atom and the like, A represents optionally substituted C6-14 aryl or optionally substituted 5 to 11 membered heteroaryl].

Pyrrolin-2-one compounds which are useful as herbicides

A cyclic amide compound of the formula: STR1 wherein X is a hydrogen atom, a halogen atom, a lower alkyl group, a haloalkyl group, a lower alkoxy group, a haloalkoxy group, a lower alkylthio group or a nitro group; Y is a hydrogen atom, a halogen atom, an