129994-50-9

Basic information

• Product Name: 8-Chloronaphthalene-1-carboxaldehyde
• Synonyms: 8-Chloronaphthalene-1-carboxaldehyde
• CAS NO: 129994-50-9
• Molecular Formula: C11H7ClO
• Molecular Weight: 190.62568
• Mol File: 129994-50-9.mol

Chemical Properties

• Boiling Point: 334.7±15.0 °C(Predicted)
• Appearance: /
• Density: 1.295±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 8-Chloronaphthalene-1-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Chloronaphthalene-1-carboxaldehyde(129994-50-9)
• EPA Substance Registry System: 8-Chloronaphthalene-1-carboxaldehyde(129994-50-9)

Safety Data

• Hazardous Substances Data: 129994-50-9(Hazardous Substances Data)

Upstream product

• 10446-06-7 8-Chlor-1-hydroxymethyl-naphthalin 
• 66-77-3 1-naphthaldehyde 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF

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A remarkably simple and efficient benzannulation reaction

(Chemical Equation Presented) On a short fuse: Although fused aromatic rings are common structural motifs in natural products, there are relatively few direct methods for the preparation of such systems from acyclic precursors. An atom-transfer radical cyclization carried out under microwave (MW) irradiation has now been developed which gives rapid access to functionalized aromatic compounds from readily available starting materials (see scheme).

PROCESS FOR SYNTHESIS OF AROMATIC COMPOUNDS

The present invention refers to a process for preparing a compound of the formula (I) wherein R denotes an organic radical which, together with the two carbon atoms to which it is bonded, forms a carbocyclic or heterocyclic ring; R1, R2, R3 and X, independently, denote hydrogen, halogen, nitro, cyano or an organic radical; or R1 and R2 or R2 and R3, together with the carbon atoms to which they are bonded, form a ring; which comprises exposing a compound of the formula (II) wherein R1, R2, R3 and X are defined as given above and Y and Z, independently, have one of the meanings of X; to an energy source in the presence of a catalyst system.

Transmission of Polar Effects. Part 18. Ionisation and Esterification with Diazodiphenylmethane of a series of 3-(8-Substituted-1-naphthyl)propiolic and (E)-3-(8-Substituted-1-naphthyl)acrylic Acids and the Alkaline Hydrolysis of the Methyl Esters of the Former Series

The pKa values of 3-(1-naphthyl)propiolic acid, together with the 8-bromo- and 8-chloro-substituted derivative, and of (E)-3-(1-naphthyl)acrylic acid together with the 8-bromo- and 8-chloro-substituted derivatives, have been determined in 80percent (w/w) 2-methoxyethanol-water at 25 deg C.The rate coefficients for the esterification of these acids with diazodiphenylmethane have been measured in 2-methoxyethanol at 30 deg C.The rate coefficients for the alkaline hydrolysis of the corresponding methyl propiolates have been determined in 70percent (v/v) dioxane-water at both 30.0 and 50.1 deg C.In the ionisation and esterification reactions, reversed dipolar substituent effects were observed.The ΔpKa values are quantitatively accounted for either by comparison with the results for simple model compounds or by Kirkwood-Westheimer calculations.The retardations observed for the effect of 8-halo substituents in the alkaline hydrolysis reaction are in agreement with a reversed dipolar effect and no steric bulk effects are observed.